• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一例起源于淋巴细胞性间质性肺炎的肺黏膜相关淋巴组织淋巴瘤

A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis.

作者信息

Park Ki Hoon, Kwon Soon Seog, Chung Myung Hee, Kim Jeana, Lee Hee Jung, Min Ji-Won, Kim Yong Hyun

机构信息

Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine, Bucheon, Korea.

出版信息

Tuberc Respir Dis (Seoul). 2012 Aug;73(2):115-21. doi: 10.4046/trd.2012.73.2.115. Epub 2012 Aug 31.

DOI:10.4046/trd.2012.73.2.115
PMID:23166544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3492375/
Abstract

Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic pulmonary lymphoproliferative disorder, such as lymphocytic interstitial pneumonitis (LIP). A recent estimate predicts that less than 5% of LIP patients acquire malignant, low-grade, B-cell lymphoma. In Korea, there has been no previous report of malignant low-grade, B-cell lymphoma, acquired from LIP. Here, we present the case of a patient with LIP that developed into pulmonary MALT lymphoma, six years after diagnosis.

摘要

肺黏膜相关淋巴组织来源（MALT）淋巴瘤是一种罕见疾病。这种疾病被认为是抗原驱动型淋巴瘤的一种模式，其由自身抗原或慢性炎症状态驱动。低度B细胞MALT淋巴瘤可能由非肿瘤性肺淋巴增殖性疾病发展而来，如淋巴细胞间质性肺炎（LIP）。最近的一项估计预测，不到5%的LIP患者会发展为恶性低度B细胞淋巴瘤。在韩国，此前尚无从LIP发展而来的恶性低度B细胞淋巴瘤的报道。在此，我们报告一例LIP患者在诊断六年后发展为肺MALT淋巴瘤的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/ac665aa4ea81/trd-73-115-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/0bfe4427ca2e/trd-73-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/2820e9c67f31/trd-73-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/b4bcd6ad6042/trd-73-115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/7506f75c686f/trd-73-115-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/ac665aa4ea81/trd-73-115-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/0bfe4427ca2e/trd-73-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/2820e9c67f31/trd-73-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/b4bcd6ad6042/trd-73-115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/7506f75c686f/trd-73-115-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe75/3492375/ac665aa4ea81/trd-73-115-g005.jpg

相似文献

1
A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis.一例起源于淋巴细胞性间质性肺炎的肺黏膜相关淋巴组织淋巴瘤
Tuberc Respir Dis (Seoul). 2012 Aug;73(2):115-21. doi: 10.4046/trd.2012.73.2.115. Epub 2012 Aug 31.
2
From lymphocytic interstitial pneumonia to MALT lymphoma of lung: a case report with a 5-year diagnostic dilemma.从淋巴细胞间质性肺炎到肺黏膜相关淋巴组织淋巴瘤：一例伴有5年诊断困境的病例报告
Int J Clin Exp Pathol. 2015 Aug 1;8(8):9698-702. eCollection 2015.
3
Pulmonary malignant lymphoma of mucosa-associated lymphoid tissue (MALT) arising in a pediatric HIV-positive patient.
Am J Surg Pathol. 1995 Mar;19(3):357-63. doi: 10.1097/00000478-199503000-00014.
4
Chemokine gene expression and clonal analysis of B cells in tissues involved by lymphoid interstitial pneumonitis from HIV-infected pediatric patients.HIV感染儿科患者淋巴间质性肺炎累及组织中B细胞的趋化因子基因表达及克隆分析
Mod Pathol. 2001 Oct;14(10):929-36. doi: 10.1038/modpathol.3880414.
5
BCL-6 mutations in pulmonary lymphoproliferative disorders: demonstration of an aberrant immunological reaction in HIV-related lymphoid interstitial pneumonia.
J Immunol. 2004 Jun 1;172(11):7116-22. doi: 10.4049/jimmunol.172.11.7116.
6
Lymphoproliferative Disorders of the Lung.肺部淋巴组织增生性疾病。
Respiration. 2017;94(2):157-175. doi: 10.1159/000477740. Epub 2017 Jun 14.
7
The spectrum of mucosa-associated lymphoid tissue lesions in pediatric patients infected with HIV: A clinicopathologic study of six cases.感染HIV的儿科患者黏膜相关淋巴组织病变谱：6例临床病理研究
Am J Clin Pathol. 1997 May;107(5):592-600. doi: 10.1093/ajcp/107.5.592.
8
Pulmonary MALT lymphoma: A case report and review of the literature.肺黏膜相关淋巴组织淋巴瘤：一例病例报告及文献综述
Exp Ther Med. 2015 Jan;9(1):147-150. doi: 10.3892/etm.2014.2072. Epub 2014 Nov 14.
9
Sjögren Syndrome Complicated by Mucosa-Associated Lymphoid Tissue Lymphoma and Lymphocytic Interstitial Pneumonia.干燥综合征合并黏膜相关淋巴组织淋巴瘤和淋巴细胞间质性肺炎。
Front Oncol. 2015 Aug 6;5:179. doi: 10.3389/fonc.2015.00179. eCollection 2015.
10
Pulmonary MALT lymphoma associated with interstitial pulmonary disease.与间质性肺疾病相关的肺黏膜相关淋巴组织淋巴瘤
Respir Med Case Rep. 2022 Jan 29;36:101598. doi: 10.1016/j.rmcr.2022.101598. eCollection 2022.

引用本文的文献

1
A case of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in a patient with a history of idiopathic lymphocytic interstitial pneumonia (iLIP).一名有特发性淋巴细胞间质性肺炎（iLIP）病史的患者发生肺黏膜相关淋巴组织（MALT）淋巴瘤的病例。
Gen Thorac Cardiovasc Surg Cases. 2025 May 9;4(1):24. doi: 10.1186/s44215-025-00208-3.

本文引用的文献

1
Update on nonneoplastic pulmonary lymphoproliferative disorders and related entities.非肿瘤性肺淋巴组织增生性疾病及相关病变的研究进展。
Arch Pathol Lab Med. 2010 May;134(5):691-701. doi: 10.5858/134.5.691.
2
Clinical characteristics and prognostic factors of pulmonary MALT lymphoma.肺黏膜相关淋巴组织淋巴瘤的临床特征和预后因素。
Eur Respir J. 2009 Dec;34(6):1408-16. doi: 10.1183/09031936.00039309. Epub 2009 Jun 18.
3
Gastric marginal zone lymphoma of MALT type: ESMO clinical recommendations for diagnosis, treatment and follow-up.
胃黏膜相关淋巴组织边缘区淋巴瘤：ESMO关于诊断、治疗及随访的临床建议
Ann Oncol. 2008 May;19 Suppl 2:ii70-1. doi: 10.1093/annonc/mdn094.
4
Marginal zone B-cell lymphoma of bronchus-associated lymphoid tissue: imaging findings in 21 patients.支气管相关淋巴组织边缘区B细胞淋巴瘤：21例患者的影像学表现
Chest. 2008 Feb;133(2):433-40. doi: 10.1378/chest.07-1956. Epub 2007 Dec 10.
5
Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation.源自边缘区B细胞的感染相关淋巴瘤：抗原驱动淋巴细胞增殖模型
Blood. 2006 Apr 15;107(8):3034-44. doi: 10.1182/blood-2005-09-3679. Epub 2006 Jan 5.
6
Pulmonary parenchymal involvement of low-grade lymphoproliferative disorders.低度淋巴增殖性疾病的肺实质受累
J Comput Assist Tomogr. 2005 Nov-Dec;29(6):825-30. doi: 10.1097/01.rct.0000179597.93844.23.
7
Lymphoid interstitial pneumonia: a narrative review.淋巴细胞间质性肺炎：一篇综述
Chest. 2002 Dec;122(6):2150-64. doi: 10.1378/chest.122.6.2150.
8
Primary pulmonary lymphoma.原发性肺淋巴瘤
Eur Respir J. 2002 Sep;20(3):750-62. doi: 10.1183/09031936.02.00404102.
9
Chemokine gene expression and clonal analysis of B cells in tissues involved by lymphoid interstitial pneumonitis from HIV-infected pediatric patients.HIV感染儿科患者淋巴间质性肺炎累及组织中B细胞的趋化因子基因表达及克隆分析
Mod Pathol. 2001 Oct;14(10):929-36. doi: 10.1038/modpathol.3880414.
10
Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses.干燥综合征患者的淋巴瘤为边缘区B细胞肿瘤，发生于不同的结外和结内部位，且与病毒无关。
Blood. 1997 Jul 15;90(2):766-75.