Wu Wei, Zhou Jing, Di Li-Gai, Chen Hui
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Medical University Xi'an, China.
Int J Clin Exp Pathol. 2015 Aug 1;8(8):9698-702. eCollection 2015.
Lymphocytic interstitial pneumonia (LIP) and mucosa-associated lymphoid tissue (MALT) lymphoma of lung are all uncommon disorders of respiratory system. MALT lymphoma of lung is a distinct and unique subtype of marginal zone B-cell non-Hodgkin's lymphoma (NHL) characterized by malignant cells arising from extranodal sites. They are characteristic of exuberant lymphoid infiltration in pathological tissue. Therefore, in some cases, they are too similar in clinical manifestation, chest imaging and pathology to make differential diagnosis. Here, we report a 43-year-old woman who underwent a tough process for the final diagnosis. From this case, we could get a well understanding of difference between LIP and MALT lymphoma of lung.
淋巴细胞间质性肺炎（LIP）和肺黏膜相关淋巴组织（MALT）淋巴瘤均为呼吸系统的罕见疾病。肺MALT淋巴瘤是边缘区B细胞非霍奇金淋巴瘤（NHL）的一种独特亚型，其特征是恶性细胞起源于结外部位。它们在病理组织中具有丰富的淋巴细胞浸润特征。因此，在某些情况下，它们在临床表现、胸部影像学和病理学方面过于相似，难以进行鉴别诊断。在此，我们报告一名43岁女性，其最终诊断经历了艰难的过程。从这个病例中，我们可以很好地了解LIP和肺MALT淋巴瘤之间的差异。
