Harhra Nasser Aa, Basaleem Huda O
Department of Surgery, Faculty of Medicine, University of Aden, Yemen.
Asian Pac J Cancer Prev. 2012;13(9):4347-51. doi: 10.7314/apjcp.2012.13.8.4247.
Breast cancer is the most common cancer of women and the principal cause of death in middle aged women. The objective of this study was to describe the trend of breast cancer and its management in Aden and adjacent south-eastern governorates of Yemen during the last 20 years.
This is a retrospective analysis of previous studies on patients with breast cancer in Aden and adjacent south-eastern governorates, Yemen (January 1989 through December 2007). The studied variables were: sex, age, time and type of presentation, disease stage, pathological types and the performed surgical treatment. The sources of information were the treatment registry of Aden health office, archives of Al-Gamhouria teaching hospital; major referral and other public and private hospitals in Aden and Aden Cancer Registry.
The total number of patients was 476, 99% being females. The age range was 19-88 years. The most affected age was 30-50 years (60.5%), 95% presenting after one month of having breast symptoms. Forty-five percent presented with signs of advanced local disease, while 59.2% had palpable axillary lymph nodes on presentation. Early breast cancer (stages I-II) occurred in 47%, and late breast cancer (stages III-IV) in 51.5%. Invasive ductal carcinoma was the commonest pathology (89.3%). The main surgical treatment was mastectomy (modified radical mastectomy (50%).
Breast cancer is predominantly a disease of young with late presentation and advanced disease. Improving health awareness and earlier diagnosis of the disease by health education, encouraging breast self-examination, and providing the mammography equipment and mammary clinics in hospitals are recommended. Establishment of oncology and radiotherapy centers in Aden is a necessity.
乳腺癌是女性最常见的癌症，也是中年女性的主要死因。本研究的目的是描述过去20年也门亚丁及邻近东南部省份乳腺癌的发病趋势及其治疗情况。
这是一项对也门亚丁及邻近东南部省份乳腺癌患者既往研究的回顾性分析（1989年1月至2007年12月）。研究变量包括：性别、年龄、就诊时间和类型、疾病分期、病理类型以及所实施的手术治疗。信息来源为亚丁卫生局治疗登记处、加姆胡里亚教学医院档案、亚丁主要转诊医院及其他公立和私立医院以及亚丁癌症登记处。
患者总数为476例，99%为女性。年龄范围为19 - 88岁。最易患病年龄为30 - 50岁（60.5%），95%在出现乳腺症状一个月后就诊。45%表现为局部晚期疾病体征，59.2%就诊时可触及腋窝淋巴结。早期乳腺癌（I - II期）占47%，晚期乳腺癌（III - IV期）占51.5%。浸润性导管癌是最常见的病理类型（89.3%）。主要手术治疗方式为乳房切除术（改良根治性乳房切除术占50%）。
乳腺癌主要是一种发生于年轻女性的疾病，就诊时病情往往较晚且已进展。建议通过健康教育提高健康意识、鼓励乳腺自我检查，并在医院配备乳腺钼靶设备和乳腺专科门诊以实现疾病的早期诊断。在亚丁建立肿瘤学和放射治疗中心很有必要。
