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比较双相情感障碍患者客观和主观评估的睡眠时间。

Comparison of objective and subjective assessments of sleep time in subjects with bipolar disorder.

机构信息

University of Texas Health Science Center San Antonio, Department of Psychiatry, San Antonio, TX 78229, USA.

出版信息

J Affect Disord. 2013 Jul;149(1-3):363-6. doi: 10.1016/j.jad.2013.02.013. Epub 2013 Mar 11.

Abstract

INTRODUCTION

Sleep disturbance is a core feature of bipolar disorder. To date there are a limited number of studies that compare subjective and objective measures of sleep in populations of subjects with mood disorders. This study evaluated the relationship between subjective and objective measurements of total sleep time (TST) in a bipolar type I disorder (BD I) population.

METHODS

Thirty-nine subjects diagnosed with BD I participated in the study. Mood symptoms were assessed via YMRS and IDS-30-C. Subjects wore an actigraph device and maintained a sleep diary for seven consecutive days. Differences between TST as estimated via sleep diaries and actigraphy were calculated.

RESULTS

Objective and subjective measures of TST were significantly correlated (r=0.5151, p=0.0008). Secondary analysis revealed that the severity of depressive symptoms did correlate to this discrepancy (t=2.65, p=0.01).

LIMITATIONS

The impact that medications have on the accuracy of TST reported was not investigated. Also, sleep diaries may have acted to prompt subjects to pay closer attention to their sleep habits and therefore more accurately report TST than in the average clinical setting.

CONCLUSION

The results of the current study demonstrate a significant correlation between the estimation of TST as measured objectively via actigraphy and subjectively via sleep diaries in BD patients. Mood symptomotology might impact the accuracy of TST reported. Further study is warranted.

摘要

简介

睡眠障碍是双相情感障碍的核心特征。迄今为止,比较心境障碍患者群体的主观和客观睡眠测量的研究数量有限。本研究评估了在 I 型双相情感障碍(BD I)人群中总睡眠时间(TST)的主观和客观测量之间的关系。

方法

39 名被诊断为 BD I 的患者参与了这项研究。通过 YMRS 和 IDS-30-C 评估情绪症状。患者佩戴活动记录仪并连续七天保持睡眠日记。通过睡眠日记和活动记录仪估计的 TST 之间的差异进行计算。

结果

TST 的客观和主观测量显著相关(r=0.5151,p=0.0008)。二次分析显示,抑郁症状的严重程度与这种差异相关(t=2.65,p=0.01)。

局限性

本研究未探讨药物对 TST 报告准确性的影响。此外,睡眠日记可能促使患者更加关注自己的睡眠习惯,从而比在一般临床环境中更准确地报告 TST。

结论

本研究的结果表明,BD 患者通过活动记录仪客观测量和通过睡眠日记主观测量的 TST 之间存在显著相关性。情绪症状可能会影响报告的 TST 的准确性。需要进一步研究。

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