Lamprou Efthymia, Kivelä Liia M M, Rohling Jos H T, Meijer Johanna H, van der Does Willem, Antypa Niki
Department of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, The Netherlands.
Department of Psychology, Panteion University of Social and Political Sciences, Athens, Greece.
Eur J Neurosci. 2024 Dec;60(11):6593-6604. doi: 10.1111/ejn.16551. Epub 2024 Oct 5.
Eveningness has been associated with both disturbed sleep and depression. It is unclear, however, if deprived sleep explains evening types' vulnerability to depression. The role of pre-sleep rumination in these associations also remains understudied. The present study assessed the relationship between eveningness and sleep quality, as well as the possible mediating effect of pre-sleep rumination and the moderating effect of a history of depression, under naturalistic conditions. Eighty-eight Dutch-speaking participants (87.5% females, 21.4 ± 3.7 years) were selected on the basis of their non-intermediate chronotype using the Morningness Eveningness Questionnaire (evening types (n = 53); morning types (n = 35)). Depression status was assessed through a diagnostic interview (healthy (n = 61); remitted depressed (n = 27)). Participants' sleep characteristics were monitored via actigraphy and sleep diaries for seven consecutive days and nights. Pre-sleep rumination was measured via a self-report questionnaire. Evening types had longer subjective and actigraphic sleep onset latency than morning types. Pre-sleep rumination did not mediate the former associations but predicted longer subjective sleep onset latency. Furthermore, the relationship between chronotype and subjective sleep onset latency was moderated by depression history. Remitted depressed evening types reported longer sleep onset latency than healthy evening and morning types, possibly posing the former at a higher risk for depressive relapse. Overall, the current findings address the need to further investigate the physiological signature of circadian rhythms and sleep latency. This could serve as a foundation for the development of prevention and early intervention programs, tailored for mood and sleep disorders.
晚睡倾向与睡眠障碍和抑郁症都有关联。然而,睡眠不足是否能解释晚睡型人群易患抑郁症的原因尚不清楚。睡前沉思在这些关联中的作用也仍未得到充分研究。本研究在自然条件下评估了晚睡倾向与睡眠质量之间的关系,以及睡前沉思可能的中介作用和抑郁症病史的调节作用。使用晨型-夜型问卷,根据非中间型昼夜节律类型选取了88名说荷兰语的参与者(87.5%为女性,年龄21.4±3.7岁)(晚睡型(n = 53);晨型(n = 35))。通过诊断访谈评估抑郁状态(健康(n = 61);缓解期抑郁症患者(n = 27))。通过活动记录仪和睡眠日记连续七天七夜监测参与者的睡眠特征。通过自我报告问卷测量睡前沉思。晚睡型参与者的主观和活动记录睡眠起始潜伏期比晨型参与者更长。睡前沉思并未介导上述关联,但可预测更长的主观睡眠起始潜伏期。此外,昼夜节律类型与主观睡眠起始潜伏期之间的关系受抑郁病史的调节。缓解期抑郁症晚睡型参与者报告的睡眠起始潜伏期比健康晚睡型和晨型参与者更长,这可能使前者有更高的抑郁复发风险。总体而言目前的研究结果表明有必要进一步研究昼夜节律和睡眠潜伏期的生理特征。这可为针对情绪和睡眠障碍量身定制的预防和早期干预项目的开发奠定基础。