Carta Mg, Petretto D, Adamo S, Bhat Km, Lecca Me, Mura G, Carta V, Angermeyer M, Moro Mf
Centro di Psichiatria di Consultazione e Psicosomatica, University of Cagliari and AOU Cagliari, Italy.
Clin Pract Epidemiol Ment Health. 2012;8:152-7. doi: 10.2174/1745017901208010152. Epub 2012 Nov 16.
To measure the effectiveness on Quality of Life of adjunctive cognitive behavioral counseling in the setting of General Practitioners (GPs) along with the treatment as usual (TAU;) for the treatment of depression.
Six month-controlled trial of patients who were referred to randomly assigned GPs (four for experimental group of patients and ten for the control) was done. Experimental sample had 34 patients with DSM-IV diagnosis of Depression (Depressed Episode, Dysthymia, or Adjustment Disorder with Depressed Mood) receiving the TAU supplemented with counseling. Control group had 30 patients with diagnosis of Depression receiving only the TAU.
The Beck Depression Inventory (BDI) score improved in both groups. Patients in the experimental group showed greater improvement compared to the control group at T2. The World Health Organization Quality OF Life Questionnaire (WHOQOL) score also improved in the experimental group but not in the control group. The improvement in the experimental group was statistically significant in terms of both BDI and WHOQOL scores.
Adding counseling to TAU in general medical practice settings is more effective in controlling the symptoms of depression and improving the quality of life as measured over a period of six months, than TAU alone. These results while encouraging, also calls for a larger study involving a largersample size and a longer period of time.
评估在全科医生(GP)环境中,辅助认知行为咨询联合常规治疗(TAU)对抑郁症治疗的生活质量效果。
对随机分配给全科医生的患者进行为期六个月的对照试验(实验组4名医生负责的患者,对照组10名医生负责的患者)。实验组有34名符合DSM-IV抑郁症诊断标准(抑郁发作、恶劣心境或伴抑郁情绪的适应障碍)的患者,接受常规治疗并辅以咨询。对照组有30名抑郁症诊断患者,仅接受常规治疗。
两组患者的贝克抑郁量表(BDI)得分均有所改善。在T2时,实验组患者的改善程度高于对照组。实验组的世界卫生组织生活质量问卷(WHOQOL)得分也有所提高,而对照组则未改善。实验组在BDI和WHOQOL得分方面的改善具有统计学意义。
在普通医疗环境中,在常规治疗基础上加用咨询,在控制抑郁症状和改善生活质量方面,比单独使用常规治疗更有效,这是在六个月的时间内测量得出的结果。这些结果虽然令人鼓舞,但也需要进行更大规模、更长时间的研究。