Mechanical Circulatory Support Program, Freeman Hospital, Newcastle upon Tyne Hospitals, NHS Foundation Trust, Newcastle upon Tyne, UK.
Eur J Cardiothorac Surg. 2013 Jun;43(6):1247-50. doi: 10.1093/ejcts/ezs585. Epub 2012 Nov 22.
Left ventricular assist device (LVAD) explantation and exchange is a relatively infrequent but potentially complex procedure. Patients requiring such procedures have multisystem suboptimal physiological reserve due to end-stage heart failure and are prone to complications. Less-invasive procedures are believed to facilitate postoperative recovery and early mobilization. We describe an alternative approach to explantation and exchange of the HeartWare LVAD through left thoracotomy.
Six patients (M = 4, F = 2, mean age = 49.16 years) underwent device explant/exchange or initial implant (explant = 2, exchange = 3, initial implant = 1) through left thoracotomy utilizing cardiopulmonary bypass and induced ventricular fibrillation (VF). The mean bypass time and mean VF arrest time were 82 and 3 min, respectively. A new outflow graft was anastomosed to the previous outflow graft in 3 cases of device exchange and to the descending aorta in 1 case of initial implant.
One patient died in the intensive care unit due to unrelated causes (gram-negative sepsis) after device exchange. All others were discharged alive and currently remain on follow-up. The mean length of hospital stay was 40.66 days.
On-pump approach through single thoracotomy incision is safe and equally suitable for device explant, exchange and initial implant. However, structural heart defects requiring surgical correction and the requirement of simultaneous right ventricular assist device are the limitations of this approach.
左心室辅助装置(LVAD)的取出和更换是一种相对少见但潜在复杂的手术。由于终末期心力衰竭,需要进行此类手术的患者多系统生理储备不佳,容易出现并发症。人们认为微创程序有助于术后恢复和早期活动。我们描述了一种通过左开胸术进行 HeartWare LVAD 取出和更换的替代方法。
6 名患者(男=4,女=2,平均年龄=49.16 岁)通过心肺转流和诱导心室颤动(VF),经左开胸术进行了设备取出/更换或初次植入(取出=2,更换=3,初次植入=1)。平均体外循环时间和平均 VF 阻断时间分别为 82 分钟和 3 分钟。在 3 例设备更换中,将新的流出管与先前的流出管吻合,在 1 例初次植入中与降主动脉吻合。
1 例患者在更换设备后因与设备无关的原因(革兰氏阴性菌败血症)死于重症监护病房。所有其他患者均存活并已出院,目前仍在随访中。平均住院时间为 40.66 天。
通过单一切口开胸的体外循环方法对于设备的取出、更换和初次植入都是安全且同样适用的。然而,需要手术矫正的结构性心脏缺陷和同时需要右心室辅助装置是该方法的局限性。