Department of Orthopaedic Surgery, UPMC Center for Sports Medicine, University of Pittsburgh, PA 15213, USA.
Clin Sports Med. 2013 Jan;32(1):93-109. doi: 10.1016/j.csm.2012.08.010.
Operative reconstruction of a torn anterior cruciate ligament (ACL) has become the most broadly accepted treatment. An important, but underreported, outcome of ACL reconstruction is graft failure, which poses a challenge for the orthopedic surgeon. An understanding of the tendon-bone healing and the intra-articular ligamentization process is crucial for orthopedic surgeons to make appropriate graft choices and to be able to initiate optimal rehabilitation protocols after surgical ACL reconstruction. This article focuses on the current understanding of the tendon-to-bone healing process for both autografts and allografts and discusses strategies to biologically augment healing.
手术重建撕裂的前交叉韧带（ACL）已成为最广泛接受的治疗方法。ACL 重建的一个重要但报道较少的结果是移植物失败，这对骨科医生来说是一个挑战。了解肌腱-骨愈合和关节内韧带化过程对于骨科医生选择合适的移植物以及在 ACL 重建手术后能够启动最佳康复方案至关重要。本文重点介绍了目前对自体移植物和同种异体移植物的肌腱-骨愈合过程的理解，并讨论了增强愈合的生物学策略。
