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经肛门内镜微创手术治疗直肠腺瘤和 T1 低危型癌。

Transanal endoscopic microsurgery in treatment of rectal adenomas and T1 low-risk carcinomas.

机构信息

Department of Cardiology, Bad Krozingen Heart Center, Südring 15, 79189, Bad Krozingen, Germany.

出版信息

World J Surg Oncol. 2012 Nov 26;10:255. doi: 10.1186/1477-7819-10-255.

Abstract

BACKGROUND

Transanal endoscopic microsurgery as a local therapy option for rectal neoplasms is a tissue-sparing technique that protects the anal sphincter. The present retrospective analysis reports the course of observation after local excision of adenomas and T1 low-risk carcinomas using transanal endoscopic microsurgery.

METHODS

In a retrospective analysis we examined data on 279 patients for local recurrence. A total of 144 patients had a rectal adenoma (n = 103) or a R0 resection of low-risk T1 carcinomas (n = 41). In this collective, we also examined parameters concerning perioperative management, complications, intraoperative blood loss and duration of hospital stay.

RESULTS

Patients with adenoma were on average 64.9 (range 37 to 90) years old; 83.5% of the adenomas were located 3 to 11 cm from the anocutaneous line. In adenoma patients the recurrence rate was 2.9% for an observation period of 21.8 months. The postoperative course was without any complications in 98.1% of patients.Patients with T1 low-risk carcinoma were 64.6 (range 30 to 89) years old. In all cases, an R0 resection could be performed. The recurrence rate was 9.8% for an observation period of 34.4 months. In this group the postoperative course was free of complications in 97.6% of patients.

CONCLUSIONS

The high efficacy of transanal endoscopic microsurgery ensures minimally invasive treatment of adenomas and low-risk T1 carcinomas with low complication rates and a low rate of therapeutic failure.

摘要

背景

经肛门内镜微创手术作为直肠肿瘤的局部治疗选择,是一种保护肛门括约肌的保留组织技术。本回顾性分析报告了经肛门内镜微创手术局部切除腺瘤和 T1 低危癌的观察结果。

方法

我们在回顾性分析中检查了 279 例患者的局部复发数据。共有 144 例患者患有直肠腺瘤(n=103)或 R0 切除低危 T1 癌(n=41)。在这一组中,我们还检查了围手术期管理、并发症、术中失血量和住院时间等参数。

结果

腺瘤患者的平均年龄为 64.9 岁(范围 37 至 90 岁);83.5%的腺瘤位于肛皮线 3 至 11 厘米处。在腺瘤患者中,观察期为 21.8 个月时的复发率为 2.9%。98.1%的患者术后无并发症。T1 低危癌患者的年龄为 64.6 岁(范围 30 至 89 岁)。所有病例均行 R0 切除。观察期为 34.4 个月时的复发率为 9.8%。在这一组中,97.6%的患者术后无并发症。

结论

经肛门内镜微创手术的高疗效确保了对腺瘤和低危 T1 癌的微创治疗,并发症发生率低,治疗失败率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3127/3556112/ec5c014af191/1477-7819-10-255-1.jpg

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