Moores UCSD Cancer Center, University of California, San Diego, La Jolla, CA 92093-0901, USA.
Psychooncology. 2013 Aug;22(8):1821-8. doi: 10.1002/pon.3219. Epub 2012 Nov 27.
Excess weight and physical inactivity are modifiable risk factors for breast cancer. Training women to use self-help resources over the internet has potential for reducing intervention costs and enhancing maintenance.
A total of 50 overweight/obese women at increased breast cancer risk were randomized to a 12-week intervention or a comparison group. Telephone-based sessions trained participants to use web-based self-monitoring tools to set goals and track diet and exercise. The comparison group received dietary information but no training. At baseline and 12 weeks, participants were weighed and wore an accelerometer.
Participants were aged 60.9 ± 0.8 years with a BMI of 33.1 ± 0.6 kg/m(2). The intervention group lost 3.3 ± 4.0 kg, whereas the comparison group gained 0.9 ± 3.4 kg (p < 0.0001). Intervention participants who found the website helpful lost 5.6 ± 0.7 kg; those who did not lost 0.8 ± 0.9 kg (p < 0.001). Change in physical activity was +70 ± 140 min/week among those who found the website helpful, -6 ± 75 min/week among those who did not, and -34 ± 207 min/week in the comparison group (p < 0.01).
A program to train women to use web-based weight loss tools achieved a substantial short-term weight loss among the majority of participants. Further follow-up is needed to assess weight loss maintenance over time.
超重和缺乏身体活动是乳腺癌的可改变风险因素。培训女性使用互联网自助资源具有降低干预成本和增强维持效果的潜力。
共有 50 名超重/肥胖且乳腺癌风险增加的女性被随机分为 12 周干预组或对照组。基于电话的课程培训参与者使用基于网络的自我监测工具来设定目标并跟踪饮食和运动。对照组仅接受饮食信息但不接受培训。在基线和 12 周时,参与者称重并佩戴加速度计。
参与者年龄为 60.9 ± 0.8 岁,BMI 为 33.1 ± 0.6 kg/m²。干预组体重减轻了 3.3 ± 4.0 公斤,而对照组体重增加了 0.9 ± 3.4 公斤(p < 0.0001)。认为网站有用的干预组参与者体重减轻了 5.6 ± 0.7 公斤;认为网站没有用的参与者体重增加了 0.8 ± 0.9 公斤(p < 0.001)。认为网站有用的参与者的身体活动变化为 +70 ± 140 分钟/周,认为网站没有用的参与者的身体活动变化为 -6 ± 75 分钟/周,对照组的身体活动变化为 -34 ± 207 分钟/周(p < 0.01)。
培训女性使用基于网络的减肥工具的方案在大多数参与者中实现了显著的短期体重减轻。需要进一步随访以评估随时间推移的体重维持情况。