Xu Ran, Du Juan, Deng Lulu, Yang Fumei, Zhang Jianxin, Wang Daoping, Zhang Yuanhu
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China.
Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(15):2286-8.
To study the chemical constituents of Periploca forrestii.
The constituents were separate using such various column chromatographic techniques as silica gel, RP-18 silica gel, MCI and Sephadex LH-20. Their structures were identified by such methods as spectral analysis.
Ten compounds were isolated and identified as periforgenin A-3-O-beta-digitoxopyranoside (1), beta-sitosterol (2), periforoside I (3), ursolic acid (4), periplogenin (5), periplocin (6), glycoside E (7), periplocoside M (8) , daucosterol (9), 2alpha, 3alpha, 23-trihydroxy-urs-12-en-28-oic acid (10).
Compound 1 was a new cardiac glycoside and compound 8 was reported for the first time from this plant.
研究大理白前的化学成分。
采用硅胶、RP - 18硅胶、MCI和葡聚糖凝胶LH - 20等多种柱色谱技术对成分进行分离。通过光谱分析等方法鉴定其结构。
分离鉴定出10个化合物，分别为大理白前苷A - 3 - O - β - 洋地黄毒糖吡喃糖苷（1）、β - 谷甾醇（2）、大理白前苷I（3）、熊果酸（4）、白前苷元（5）、杠柳毒苷（6）、糖苷E（7）、大理白前苷M（8）、胡萝卜苷（9）、2α，3α，23 - 三羟基 - 乌苏 - 12 - 烯 - 28 - 酸（10）。
化合物1为新的强心苷，化合物8首次从该植物中报道。
