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职业性噪声暴露与高血压的风险。

Occupational noise exposure and the risk of hypertension.

机构信息

Danish Ramazzini Centre, Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark.

出版信息

Epidemiology. 2013 Jan;24(1):135-42. doi: 10.1097/EDE.0b013e31826b7f76.

Abstract

BACKGROUND

Noise may increase the risk of hypertension, but findings are inconsistent with respect to both community and occupational noise exposure. We used a large sample of noise-exposed industrial trades to analyze the association of occupational noise exposure and the risk of hypertension.

METHODS

The 7-year prospective cohort study included 145,190 workers from 625 companies representing 10 industrial trades and 100 companies from the finance sector. They were followed from 2001 to 2007 by record linkage with several Danish national registries. Full-shift noise exposure levels, measured in a random subset of 710 workers at the start and the end of follow-up, ranged from 70 to 86 dB(A); based on this information, historical levels back to the 1960s were estimated. Hypertension (defined by the prescription of antihypertensive medication or a hospital discharge diagnosis of hypertension) was regressed on the trade mean sound levels (LAEq) adjusting for a number of covariates.

RESULTS

Women had increased rate ratios for hypertension when comparing blue-collar industrial workers with white-collar financial workers (adjusted rate ratio = 1.17 [95% confidence interval = 1.09-1.26]). For men, the corresponding relative risk value was 1.06 (0.98-1.14). Within blue-collar industrial workers, however, increasing noise exposure level was not associated with an increasing risk of hypertension among either men or women.

CONCLUSION

Our study shows no increased risk of hypertension with exposure to noise in the lower half of the 80-90 dB(A) range.

摘要

背景

噪音可能会增加患高血压的风险,但关于社区和职业噪音暴露,其结果并不一致。我们使用大量暴露于噪音的工业行业样本,分析职业性噪声暴露与高血压风险之间的关系。

方法

这项为期 7 年的前瞻性队列研究包括来自 625 家公司的 145190 名工人,代表 10 个工业行业和 100 家金融行业的公司。从 2001 年到 2007 年,通过与几个丹麦国家登记处的记录链接对他们进行了随访。在 710 名工人的随机子集中测量了整个班次的噪声暴露水平,范围从 70 到 86 dB(A);基于此信息,估算了可追溯到 20 世纪 60 年代的历史水平。高血压(定义为服用抗高血压药物或医院诊断为高血压)的回归分析基于贸易平均声级(LAeq),并调整了许多协变量。

结果

与白领金融工人相比,蓝领工人患高血压的比率比(调整后的比率比=1.17[95%置信区间=1.09-1.26])更高。对于男性,相应的相对风险值为 1.06(0.98-1.14)。然而,在蓝领工人中,噪声暴露水平的增加与男性或女性患高血压的风险增加无关。

结论

我们的研究表明,在 80-90dB(A)范围内的较低噪声水平下,暴露于噪声中不会增加患高血压的风险。

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