Shimizu Taro, Yoshida Tsuneyasu, Kitamura Koichi, Hamada Osamu
Department of General Medicine, Nerima Hikarigaoka Hospital, Tokyo, Japan.
BMJ Case Rep. 2012 Nov 28;2012:bcr2012007559. doi: 10.1136/bcr-2012-007559.
A 91-year-old man with chronic low-back pain presented with 1-day history of disturbance of consciousness and myoclonus of all of his extremities and face. Laboratory examinations revealed no abnormalities. Administration of benzodiazepine for the myoclonus resulted in immediate and complete disappearance of the symptoms. He recently started taking pregabalin (Lyrica capsules) which was prescribed for low-back pain 3 days ago. The day following admission, he discontinued pregabalin. He did not experience recurrence of his symptoms any more. We concluded that the neurological symptoms he experienced were possibly due to pregabalin.
一名91岁的慢性下背痛男性患者，出现意识障碍及四肢和面部肌阵挛1天。实验室检查未发现异常。使用苯二氮䓬类药物治疗肌阵挛后，症状立即完全消失。他最近开始服用普瑞巴林（乐瑞卡胶囊），该药是3天前因下背痛而开具的。入院次日，他停用了普瑞巴林。此后他未再出现症状复发。我们得出结论，他所经历的神经症状可能是由普瑞巴林引起的。
