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是否治疗:辅助放射性碘治疗在甲状腺癌患者中的作用。

To treat or not to treat: the role of adjuvant radioiodine therapy in thyroid cancer patients.

机构信息

Department of Surgery, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA.

出版信息

J Oncol. 2012;2012:707156. doi: 10.1155/2012/707156. Epub 2012 Nov 1.

DOI:10.1155/2012/707156
PMID:23193402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3502018/
Abstract

Radioactive iodine (RAI) is used in treatment of patients with differentiated papillary and follicular thyroid cancer. It is typically used after thyroidectomy, both as a means of imaging to detect residual thyroid tissue or metastatic disease, as well as a means of treatment by ablation if such tissue is found. In this paper, we discuss the indications for and the mechanisms of RAI in the treatment of patients with thyroid cancer. We discuss the attendant risks and benefits that come with its use, as well as techniques used to optimize its effectiveness as an imaging tool and a therapeutic modality.

摘要

放射性碘(RAI)用于治疗分化型甲状腺癌(乳头状和滤泡状甲状腺癌)患者。RAI 通常在甲状腺切除术后使用,既是为了发现残留甲状腺组织或转移病灶而进行的成像手段,也是为了对这些组织进行消融治疗而使用的手段。本文讨论了 RAI 在甲状腺癌治疗中的适应证和作用机制,讨论了使用 RAI 带来的风险和获益,以及用于优化其作为成像工具和治疗方式的有效性的技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9252/3502018/d0eea2ea8c23/JO2012-707156.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9252/3502018/d0eea2ea8c23/JO2012-707156.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9252/3502018/d0eea2ea8c23/JO2012-707156.001.jpg

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N Engl J Med. 2012 May 3;366(18):1674-85. doi: 10.1056/NEJMoa1109589.
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Strategies of radioiodine ablation in patients with low-risk thyroid cancer.低危甲状腺癌患者的碘 131 消融策略。
J Med Chem. 2025 Feb 13;68(3):2356-2376. doi: 10.1021/acs.jmedchem.4c02885. Epub 2025 Feb 2.
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Endocrinol Metab (Seoul). 2025 Apr;40(2):201-215. doi: 10.3803/EnM.2024.2033. Epub 2025 Jan 22.
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Racial-Ethnic Comparison of Treatment for Papillary Thyroid Cancer in the Military Health System.种族-民族比较在军事卫生系统中治疗甲状腺乳头状癌。
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