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小鼠肺炎病毒的分子克隆

Molecular cloning of pneumonia virus of mice.

作者信息

Chambers P, Barr J, Pringle C R, Easton A J

机构信息

Department of Biological Sciences, University of Warwick, Coventry, United Kingdom.

出版信息

J Virol. 1990 Apr;64(4):1869-72. doi: 10.1128/JVI.64.4.1869-1872.1990.

DOI:10.1128/JVI.64.4.1869-1872.1990
PMID:2319655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC249333/
Abstract

cDNA clones representing nine genes of pneumonia virus of mice (PVM) have been generated. The sizes of the corresponding mRNAs and a provisional transcriptional map of the virus genome have been determined. The apparent gene order is very similar to that of respiratory syncytial virus. The sequences adjacent to the 3' termini of the PVM genes were determined and are very similar to those of respiratory syncytial virus. Several PVM gene polypeptide products have been assigned.

摘要

已生成代表小鼠肺炎病毒(PVM)九个基因的cDNA克隆。已确定了相应mRNA的大小和病毒基因组的临时转录图谱。明显的基因顺序与呼吸道合胞病毒非常相似。确定了PVM基因3'末端附近的序列,这些序列与呼吸道合胞病毒的序列非常相似。已确定了几种PVM基因多肽产物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b9/249333/8872c4041932/jvirol00059-0463-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b9/249333/b366c182ca44/jvirol00059-0462-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b9/249333/8872c4041932/jvirol00059-0463-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b9/249333/b366c182ca44/jvirol00059-0462-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b9/249333/8872c4041932/jvirol00059-0463-a.jpg

相似文献

1
Molecular cloning of pneumonia virus of mice.小鼠肺炎病毒的分子克隆
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2
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2
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本文引用的文献

1
A VIRUS RECOVERED FROM PATIENTS WITH PRIMARY ATYPICAL PNEUMONIA.从原发性非典型肺炎患者体内分离出的一种病毒。
Science. 1943 Mar 26;97(2517):289-91. doi: 10.1126/science.97.2517.289.
2
Coding assignments of the five smaller mRNAs of Newcastle disease virus.新城疫病毒五种较小mRNA的编码分配
J Virol. 1982 Sep;43(3):1024-31. doi: 10.1128/JVI.43.3.1024-1031.1982.
3
Non-structural proteins in Newcastle disease virus-infected cells.新城疫病毒感染细胞中的非结构蛋白。
小鼠肺炎病毒磷蛋白基因序列:来自两个重叠阅读框的多种蛋白质的表达。
J Virol. 1994 Aug;68(8):5330-4. doi: 10.1128/JVI.68.8.5330-5334.1994.
4
Cloning and sequencing of the matrix protein (M) gene of turkey rhinotracheitis virus reveal a gene order different from that of respiratory syncytial virus.火鸡鼻气管炎病毒基质蛋白(M)基因的克隆与测序显示,其基因排列顺序与呼吸道合胞病毒不同。
Virology. 1992 Feb;186(2):426-34. doi: 10.1016/0042-6822(92)90007-c.
J Gen Virol. 1982 Jan;58 Pt 1:1-12. doi: 10.1099/0022-1317-58-1-1.
4
Nucleotide sequence of the gene encoding respiratory syncytial virus matrix protein.编码呼吸道合胞病毒基质蛋白的基因的核苷酸序列。
J Virol. 1984 Apr;50(1):92-9. doi: 10.1128/JVI.50.1.92-99.1984.
5
Identification of a tenth mRNA of respiratory syncytial virus and assignment of polypeptides to the 10 viral genes.呼吸道合胞病毒第十种mRNA的鉴定及多肽与10个病毒基因的对应关系
J Virol. 1984 Feb;49(2):572-8. doi: 10.1128/JVI.49.2.572-578.1984.
6
Prevalence of indigenous viruses in laboratory animal colonies in the United Kingdom 1978-1979.
Lab Anim. 1980 Oct;14(4):309-11. doi: 10.1258/002367780781071003.
7
Polycistronic vesicular stomatitis virus RNA transcripts.多顺反子水泡性口炎病毒RNA转录本。
Proc Natl Acad Sci U S A. 1980 Aug;77(8):4662-5. doi: 10.1073/pnas.77.8.4662.
8
Monoclonal antibodies to human respiratory syncytial virus and their use in comparison of different virus isolates.抗人呼吸道合胞病毒单克隆抗体及其在不同病毒分离株比较中的应用。
J Gen Virol. 1984 May;65 ( Pt 5):963-71. doi: 10.1099/0022-1317-65-5-963.
9
A simple and very efficient method for generating cDNA libraries.一种简单且非常有效的生成cDNA文库的方法。
Gene. 1983 Nov;25(2-3):263-9. doi: 10.1016/0378-1119(83)90230-5.
10
cDNA cloning and transcriptional mapping of nine polyadenylylated RNAs encoded by the genome of human respiratory syncytial virus.人呼吸道合胞病毒基因组编码的9种多聚腺苷酸化RNA的cDNA克隆及转录图谱分析
Proc Natl Acad Sci U S A. 1983 Jun;80(11):3208-12. doi: 10.1073/pnas.80.11.3208.