小鼠肺炎病毒的分子克隆
Molecular cloning of pneumonia virus of mice.
作者信息
Chambers P, Barr J, Pringle C R, Easton A J
机构信息
Department of Biological Sciences, University of Warwick, Coventry, United Kingdom.
出版信息
J Virol. 1990 Apr;64(4):1869-72. doi: 10.1128/JVI.64.4.1869-1872.1990.
cDNA clones representing nine genes of pneumonia virus of mice (PVM) have been generated. The sizes of the corresponding mRNAs and a provisional transcriptional map of the virus genome have been determined. The apparent gene order is very similar to that of respiratory syncytial virus. The sequences adjacent to the 3' termini of the PVM genes were determined and are very similar to those of respiratory syncytial virus. Several PVM gene polypeptide products have been assigned.
已生成代表小鼠肺炎病毒（PVM）九个基因的cDNA克隆。已确定了相应mRNA的大小和病毒基因组的临时转录图谱。明显的基因顺序与呼吸道合胞病毒非常相似。确定了PVM基因3'末端附近的序列，这些序列与呼吸道合胞病毒的序列非常相似。已确定了几种PVM基因多肽产物。
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