Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Victoria, Australia.
Int Psychogeriatr. 2013 Mar;25(3):456-66. doi: 10.1017/S1041610212001986. Epub 2012 Dec 3.
Anxiety and depression contribute to morbidity in elderly adults and may be associated with diet. We investigated the association between diet and psychological distress as a marker for depression.
Dietary patterns were defined by factor analysis or the Mediterranean Diet Score (MDS); depression and anxiety were assessed 12 years later. A total of 8,660 generally healthy men and women born in Australia and aged 50-69 years from the Melbourne Collaborative Cohort Study were included. At baseline (1990-1994), diet (food frequency questionnaire), education, Socio-Economic Indexes for Areas (SEIFA) - Index of Relative Socio-economic Disadvantage, medication use, social engagement, physical activity, smoking status, alcohol use, and health conditions were assessed; at follow-up (2003-2007), psychological distress was assessed using the Kessler Psychological Distress Scale (K10). Logistic regression was used to identify associations between diet and a K10 score ≥20, indicative of psychological distress.
The MDS was inversely associated with psychological distress, with the odds ratio in the top-scoring group relative to the lowest scoring group being 0.72 (95% confidence interval = 0.54-0.95). Stronger adherence to a traditional Australian-style eating pattern was also associated with a lower K10 score at follow-up, with the odds ratio for having a K10 score indicative of psychological distress for the top 20% of adherence to this pattern relative to the lowest being 0.61 (95% confidence interval = 0.40-0.91).
A Mediterranean-style diet was associated with less psychological distress, possibly through provision of a healthy nutrient profile. The Australian dietary pattern, which included some foods high in fat and sugar content along with whole foods, also showed a weak inverse association. Adherence to this pattern may reflect a feeling of belonging to the community associated with less psychological distress.
焦虑和抑郁会导致老年人的发病率增加,并且可能与饮食有关。我们研究了饮食与心理困扰之间的关系,后者可作为抑郁的标志物。
采用因子分析或地中海饮食评分(MDS)来定义饮食模式;12 年后评估抑郁和焦虑情况。总共纳入了 8660 名来自澳大利亚墨尔本协作队列研究、年龄在 50-69 岁之间、一般健康的男性和女性。在基线(1990-1994 年)时评估了饮食(食物频率问卷)、教育程度、社会经济区域指数(SEIFA)-相对社会经济劣势指数、药物使用、社会参与度、身体活动、吸烟状况、饮酒情况和健康状况;在随访(2003-2007 年)时使用 Kessler 心理困扰量表(K10)评估心理困扰情况。采用逻辑回归来确定饮食与 K10 评分≥20(表示心理困扰)之间的关联。
MDS 与心理困扰呈负相关,评分最高组相对于最低组的比值比为 0.72(95%置信区间=0.54-0.95)。更严格地遵循传统澳大利亚式饮食模式也与随访时的 K10 评分较低相关,对这种模式的最高 20%的依从性相对于最低依从性,K10 评分表示心理困扰的比值比为 0.61(95%置信区间=0.40-0.91)。
地中海式饮食与较少的心理困扰相关,这可能是通过提供健康的营养谱来实现的。包括一些高脂肪和高糖含量食物以及全食物的澳大利亚饮食模式也显示出较弱的负相关关系。对这种模式的依从性可能反映了与较少心理困扰相关的社区归属感。