Research & Development, Laboratorios LETI S.L., Calle del Sol 5, 28760 Tres Cantos, Madrid, Spain.
Food Chem. 2013 Apr 15;137(1-4):130-5. doi: 10.1016/j.foodchem.2012.10.005. Epub 2012 Oct 22.
Goji berries (GB) have been introduced in Western diet. Preliminary reports have demonstrated its allergenic capacity. The objectives of the study were to investigate the frequency of sensitisation and the allergens involved. 566 individuals, with respiratory or cutaneous symptoms were skin-prick tested with GB extract. Thirty three were positive (5.8%). 94% were sensitised to other allergens. Specific IgE to GB, peach, tomato and nut-mix was measured. Thirteen individuals from 24 available sera (54.2%) had positive specific IgE. 92.3% of GB positive patients were positive to peach. Seven individuals recognised 8 bands and six recognised a 7kDa band. This band was identified as a LTP by MS/MS. Cross-reactivity was demonstrated with tomato, tobacco, nutmix, Artemisia pollen and purified Lyc e 3 and Pru p 3. GB are a new allergenic source with high prevalence of sensitisation. LTP seems to be the major allergen involved in sensitisation and cross-reactivity.
枸杞（GB）已被引入西方饮食。初步报告表明其具有致敏能力。本研究的目的是调查致敏的频率和涉及的过敏原。对 566 名有呼吸道或皮肤症状的个体进行了枸杞提取物的皮肤点刺试验。33 人呈阳性（5.8%）。94%的人对其他过敏原过敏。测量了枸杞、桃、番茄和坚果混合物的特异性 IgE。从 24 份可获得的血清中，有 13 份（54.2%）特异性 IgE 呈阳性。92.3%的枸杞阳性患者对桃呈阳性。7 人识别出 8 条带，6 人识别出 7kDa 带。该带通过 MS/MS 鉴定为 LTP。与番茄、烟草、坚果混合物、蒿属花粉和纯化的 Lyc e 3 和 Pru p 3 表现出交叉反应。枸杞是一种新的过敏原来源，具有高致敏率。LTP 似乎是致敏和交叉反应中涉及的主要过敏原。
