Department of Physiology and Biophysics and the Gruss Magnetic Resonance Research Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
Am J Pathol. 2013 Feb;182(2):296-304. doi: 10.1016/j.ajpath.2012.09.026. Epub 2012 Nov 28.
Infectious diseases are the second leading cause of death worldwide. Noninvasive small-animal imaging has become an important research tool for preclinical studies of infectious diseases. Imaging studies permit enhanced information through longitudinal studies of the same animal during the infection. Herein, we briefly review recent studies of animal models of infectious disease that have used imaging modalities.
传染病是全球第二大致死原因。非侵入性小动物成像已成为传染病临床前研究的重要研究工具。通过对感染期间同一动物进行纵向研究,可以获得更丰富的信息。本文简要综述了近年来使用成像方式研究动物传染病模型的研究。