Universidade Federal do Ceará, R. Cel Nunes de Melo 1315-Rodolfo Teófilo, Fortaleza, Ceará, CEP 60.430-270, Brazil.
Endocrine. 2013 Aug;44(1):125-31. doi: 10.1007/s12020-012-9841-6. Epub 2012 Dec 1.
To evaluate the relationship between physical activity with co morbidities and health-related quality of life in type 2 diabetic patients with and without restless legs syndrome (RLS). This is an observational study, set at tertiary care diabetic outpatient clinic, where 200 consecutive type 2 diabetic patients and 47 controls participated. Physical activity level was established by the International Physical Activity Questionnaire (IPAQ) and RLS diagnosis and RLS severity were established using the criteria defined by the International Restless Legs Syndrome Study Group; excessive daytime sleepiness was evaluated by the Epworth Sleepiness Scale, quality of sleep by the Pittsburgh Sleep Quality Index and Health-Related Quality of Life by the Short-Form Health Survey (SF-36). Depressive symptoms were investigated by Beck Depression Inventory (BDI- II). Among all diabetic patients (58 % women, mean age 52.7 ± 5.7), disease duration varied from 1 to 30 years (11.7 ± 7.5). Diabetic patients had more hypertension (76 %), peripheral neuropathy (65 %), and depressive symptoms (31 %) than controls; no gender differences were found between cases with and without depressive symptoms. RLS patients (72 % female) had worse quality of sleep. With regards to the quality of life domains, more active RLS diabetic patients had better perception of functional capacity, physical limitation, pain, and general health state (p < 0.05). RLS symptom severity did not vary according to physical activity (IPAQ level). This study shows that the physical activity is associated with a better perception of functional capacity, physical limitation, and pain in diabetic patients with RLS; thus a more active lifestyle should be encouraged.
评估 2 型糖尿病伴或不伴不安腿综合征（RLS）患者的身体活动与合并症及健康相关生活质量之间的关系。这是一项观察性研究，在三级保健糖尿病门诊进行，共有 200 例连续 2 型糖尿病患者和 47 例对照者参与。身体活动水平由国际体力活动问卷（IPAQ）确定，RLS 诊断和 RLS 严重程度采用国际不安腿综合征研究组定义的标准确定；白天过度嗜睡通过 Epworth 嗜睡量表评估，睡眠质量通过匹兹堡睡眠质量指数评估，健康相关生活质量通过简明健康调查问卷（SF-36）评估。通过贝克抑郁量表（BDI- II）评估抑郁症状。在所有糖尿病患者中（58%为女性，平均年龄 52.7±5.7 岁），疾病病程从 1 年到 30 年不等（11.7±7.5 年）。与对照组相比，糖尿病患者有更多的高血压（76%）、周围神经病变（65%）和抑郁症状（31%）；但在有或没有抑郁症状的病例之间没有发现性别差异。RLS 患者（72%为女性）的睡眠质量更差。关于生活质量领域，更活跃的 RLS 糖尿病患者对身体机能、身体受限、疼痛和一般健康状况的感知更好（p<0.05）。RLS 症状严重程度与身体活动（IPAQ 水平）无关。这项研究表明，身体活动与 RLS 糖尿病患者的身体机能、身体受限和疼痛感知更好相关；因此，应鼓励更积极的生活方式。
