Pearson P A, Baldwin L B, Smith T J
University of Kentucky, Department of Opthalmology, Lexington.
Ophthalmologica. 1990;200(1):16-21. doi: 10.1159/000310072.
Statistical analysis of visual-field data is permitted by the quantitative techniques used in automated perimetry. The visual-field indices mean defect (MD) and corrected loss variance (CLV) provide an opportunity to analyze and follow visual fields mathematically. We investigated the relationship of MD to CLV in 32 glaucoma suspects and 17 patients with visual-field defects due to chronic open-angle glaucoma. In glaucoma patients with early and moderate disease (up to a MD of 18 dB), the CLV statistically covaried with the MD (R2 = 0.85). Beyond an MD of 18 dB, increases in the MD seemed to cause a decline in the CLV. These results differ from prior reports on the relationship of MD and CLV. Reasons for this and implications for the use of these statistics in the clinical management of the glaucoma patient are discussed. These results may be helpful in the understanding of the pathophysiologic basis of damage in glaucoma.
自动视野计所使用的定量技术允许对视野数据进行统计分析。视野指标平均缺损（MD）和校正损失方差（CLV）为从数学角度分析和跟踪视野提供了机会。我们研究了32名青光眼疑似患者和17名因慢性开角型青光眼导致视野缺损的患者中MD与CLV的关系。在早期和中度疾病（MD高达18 dB）的青光眼患者中，CLV与MD存在统计学协变关系（R2 = 0.85）。超过18 dB的MD后，MD的增加似乎会导致CLV下降。这些结果与之前关于MD和CLV关系的报告不同。本文讨论了造成这种情况的原因以及这些统计数据在青光眼患者临床管理中的应用意义。这些结果可能有助于理解青光眼损害的病理生理基础。
