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INDICO：一项针对经历社会经济转型的印度人群进行表观基因组学研究资源的开发。

INDICO: the development of a resource for epigenomic study of Indians undergoing socioeconomic transition.

出版信息

Hugo J. 2011 Dec;5(1-4):65-9. doi: 10.1007/s11568-011-9157-2. Epub 2011 Nov 22.

DOI:10.1007/s11568-011-9157-2
PMID:23205164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3238020/
Abstract

UNLABELLED

The INdian DIabetes COnsortium (INDICO) is an initiative to build a resource for genetic, epigenetic and clinical studies of type 2 diabetes (T2D) in socioeconomically transiting Indians. The consortium aims to follow selected communities which are undergoing rapid urbanization over a period of years to create a knowledge base for the better understanding of the gene-environment interaction in T2D. These resources can eventually be of value to not just the diabetes research community but would be able to contribute towards an improved understanding, diagnosis and prevention of numerous complex human disorders.

ELECTRONIC SUPPLEMENTARY MATERIAL

The online version of this article (doi:10.1007/s11568-011-9157-2) contains supplementary material, which is available to authorized users.

摘要

未标注

印度糖尿病联盟（INDICO）是一项旨在为社会经济转型期的印度人建立2型糖尿病（T2D）基因、表观遗传和临床研究资源的倡议。该联盟旨在追踪选定的正在经历快速城市化的社区，历时数年以创建一个知识库，以便更好地理解T2D中的基因-环境相互作用。这些资源最终不仅对糖尿病研究界有价值，而且能够有助于更好地理解、诊断和预防众多复杂的人类疾病。

电子补充材料

本文的在线版本（doi:10.1007/s11568-011-9157-2）包含补充材料，授权用户可获取。

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本文引用的文献

1
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N Engl J Med. 2010 Dec 9;363(24):2339-50. doi: 10.1056/NEJMra0906948.
2
Epigenetic changes in early life and future risk of obesity.早期生活中的表观遗传变化与肥胖的未来风险。
Int J Obes (Lond). 2011 Jan;35(1):72-83. doi: 10.1038/ijo.2010.122. Epub 2010 Jun 15.
3
Evaluation of DOK5 as a susceptibility gene for type 2 diabetes and obesity in North Indian population.评价 DOK5 作为北印度人群 2 型糖尿病和肥胖的易感性基因。
BMC Med Genet. 2010 Feb 27;11:35. doi: 10.1186/1471-2350-11-35.
4
Gene prioritization in Type 2 Diabetes using domain interactions and network analysis.使用域交互和网络分析进行 2 型糖尿病的基因优先级排序。
BMC Genomics. 2010 Feb 2;11:84. doi: 10.1186/1471-2164-11-84.
5
The IDF Diabetes Atlas: providing evidence, raising awareness and promoting action.国际糖尿病联盟糖尿病地图集：提供证据、提高认识并促进行动。
Diabetes Res Clin Pract. 2010 Jan;87(1):2-3. doi: 10.1016/j.diabres.2009.11.006. Epub 2009 Dec 4.
6
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J Hum Genet. 2008;53(11-12):957-965. doi: 10.1007/s10038-008-0335-6. Epub 2008 Sep 17.
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