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戒断期海洛因依赖者估值网络之间的功能连接失衡。

Imbalanced functional link between valuation networks in abstinent heroin-dependent subjects.

作者信息

Xie C, Shao Y, Ma L, Zhai T, Ye E, Fu L, Bi G, Chen G, Cohen A, Li W, Chen G, Yang Z, Li S-J

机构信息

1] Cognitive and Mental Health Research Center, Beijing Institute of Basic Medical Science, Beijing, China [2] Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA.

Cognitive and Mental Health Research Center, Beijing Institute of Basic Medical Science, Beijing, China.

出版信息

Mol Psychiatry. 2014 Jan;19(1):10-2. doi: 10.1038/mp.2012.169. Epub 2012 Dec 4.

DOI:10.1038/mp.2012.169
PMID:23207652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4524350/
Abstract

Using neuroeconomic approaches, our findings demonstrate that the underlying duality of the β-δ discounting networks that jointly influence valuation is impaired to a pathogenic state in abstinent heroin dependents. The imbalanced functional link between the β-δ networks for valuation may orchestrate the irrational choice in drug addiction.

摘要

运用神经经济学方法,我们的研究结果表明,共同影响估值的β-δ贴现网络的潜在二元性在戒断的海洛因依赖者中受损至致病状态。用于估值的β-δ网络之间功能联系的失衡可能在药物成瘾中协调非理性选择。

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