环腺苷酸途径。
The cyclic AMP pathway.
机构信息
Center for Epigenetics and Metabolism, School of Medicine, University of California, Irvine, CA 92697, USA.
出版信息
Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148. doi: 10.1101/cshperspect.a011148.
Abstract
cAMP was the first second messenger to be identified. Its three main effectors are PKA (which phosphorylates numerous metabolic enzymes), EPAC (a guanine-nucleotide-exchange factor), and cyclic-nucleotide-gated ion channels.
摘要
cAMP 是第一个被鉴定的第二信使。其三个主要效应物是 PKA（磷酸化许多代谢酶）、EPAC（鸟苷酸交换因子）和环核苷酸门控离子通道。
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