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环腺苷酸途径。

The cyclic AMP pathway.

机构信息

Center for Epigenetics and Metabolism, School of Medicine, University of California, Irvine, CA 92697, USA.

出版信息

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148. doi: 10.1101/cshperspect.a011148.

DOI:10.1101/cshperspect.a011148
PMID:23209152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3504441/
Abstract

cAMP was the first second messenger to be identified. Its three main effectors are PKA (which phosphorylates numerous metabolic enzymes), EPAC (a guanine-nucleotide-exchange factor), and cyclic-nucleotide-gated ion channels.

摘要

cAMP 是第一个被鉴定的第二信使。其三个主要效应物是 PKA（磷酸化许多代谢酶）、EPAC（鸟苷酸交换因子）和环核苷酸门控离子通道。

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本文引用的文献

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Cell Signal. 2005 Jul;17(7):789-97. doi: 10.1016/j.cellsig.2004.12.017.
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AKAP signalling complexes: focal points in space and time.A激酶附着蛋白信号复合物：时空焦点
Nat Rev Mol Cell Biol. 2004 Dec;5(12):959-70. doi: 10.1038/nrm1527.
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Crosstalk between cAMP and Ca2+ signaling in non-excitable cells.非兴奋性细胞中cAMP与Ca2+信号之间的相互作用。
Cell Calcium. 2003 Dec;34(6):431-44. doi: 10.1016/s0143-4160(03)00150-7.
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Epac: a new cAMP target and new avenues in cAMP research.Epac：一种新的环磷酸腺苷（cAMP）靶点及cAMP研究的新途径。
Nat Rev Mol Cell Biol. 2003 Sep;4(9):733-8. doi: 10.1038/nrm1197.
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Fractionation and characterization of a cyclic adenine ribonucleotide formed by tissue particles.由组织颗粒形成的环状腺嘌呤核糖核苷酸的分级分离与特性鉴定
J Biol Chem. 1958 Jun;232(2):1077-91.
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CAMP and Ca2+ interplay: a matter of oscillation patterns.环磷酸腺苷（CAMP）与钙离子（Ca2+）的相互作用：振荡模式问题
Trends Neurosci. 2003 Feb;26(2):53-5. doi: 10.1016/s0166-2236(02)00017-6.
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Seven-transmembrane receptors.七跨膜受体
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Cyclic AMP signalling.环磷酸腺苷信号传导
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