Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.
Am J Gastroenterol. 2012 Dec;107(12):1777-83. doi: 10.1038/ajg.2012.140.
We compared reported reasons for participation and nonparticipation in colorectal cancer (CRC) screening between colonoscopy and computed tomographic (CT) colonography in a randomized controlled trial.
We randomly invited 8,844 people for screening by colonoscopy or CT colonography. On a questionnaire, invitees indicated reasons for participation or nonparticipation and indicated the most decisive reason.
The most frequently cited reasons to accept screening were early detection of precursor lesions and CRC, and contribution to science. The most frequently cited reasons to decline were the unpleasantness of the examination, the inconvenience of the preparation, a lack of symptoms, and "no time/too much effort." Among colonoscopy nonparticipants, elderly invitees cited inconvenience less often, and absence of symptoms more often, than did the group overall. The reason reported most frequently as the most decisive reason not to participate was the unpleasantness of the examination among colonoscopy nonparticipants, and "no time/too much effort" and lack of symptoms among CT colonography nonparticipants.
In light of these results, future screening programs could tailor the information provided to invitees.
我们在一项随机对照试验中比较了结肠镜检查和计算机断层扫描（CT）结肠成像两种结直肠癌（CRC）筛查方法的参与者和非参与者报告的参与原因和不参与原因。
我们随机邀请了 8844 人进行结肠镜检查或 CT 结肠成像筛查。在一份问卷中，受邀者表示了参与或不参与的原因，并指出了最具决定性的原因。
最常被引用的接受筛查的原因是早期发现癌前病变和 CRC，以及对科学的贡献。最常被引用的拒绝原因是检查的不适、准备的不便、无症状和“没有时间/太麻烦”。在结肠镜检查非参与者中，年长的受邀者比总体人群更少地提到不便，而更多地提到无症状。报告的最不参与的决定性原因是非结肠镜检查参与者的检查不适，以及 CT 结肠成像非参与者的“没有时间/太麻烦”和无症状。
鉴于这些结果，未来的筛查计划可以根据受邀者的情况提供个性化的信息。
