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同一供体的两名受者因念珠菌血管并发症导致肾移植失败。

Loss of renal allografts secondary to Candida vascular complications in two recipients from the same donor.

作者信息

Yannam Govardhana Rao, Wrenshall Lucile, Stevens R Brian

机构信息

Transplant Surgery Division, Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198-3285, USA.

出版信息

Case Rep Transplant. 2012;2012:364735. doi: 10.1155/2012/364735. Epub 2012 Mar 7.

DOI:10.1155/2012/364735
PMID:23213612
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3504265/
Abstract

Infections remain a major cause of morbidity and mortality in transplant patients. Organ recipients are also susceptible to donor-derived pathogens and the majority of donor infections are easily treatable. Rarely, some pathogens have produced life-threatening complications by compromising the vascular anastomosis. In this case series we report loss of two kidney allografts secondary to vascular complications due to Candida albicans. Both recipients received grafts from a common donor, in whom Candida bacteremia in the donor was not apparent at the time of organ acceptance but became apparent on delayed cultures.

摘要

感染仍然是移植患者发病和死亡的主要原因。器官接受者也易感染来自供体的病原体,并且大多数供体感染易于治疗。极少数情况下,一些病原体通过破坏血管吻合术产生危及生命的并发症。在本病例系列中,我们报告了两例因白色念珠菌引起血管并发症导致肾移植失败的病例。两名接受者均接受了来自同一供体的移植物,该供体在器官接受时念珠菌血症并不明显,但在延迟培养时变得明显。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ec/3504265/df75819ddb74/CRIM.TRANSPLANTATION2012-364735.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ec/3504265/f6096ec0fd74/CRIM.TRANSPLANTATION2012-364735.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ec/3504265/df75819ddb74/CRIM.TRANSPLANTATION2012-364735.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ec/3504265/f6096ec0fd74/CRIM.TRANSPLANTATION2012-364735.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ec/3504265/df75819ddb74/CRIM.TRANSPLANTATION2012-364735.002.jpg

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本文引用的文献

1
Outcome of renal transplantation in eight patients with Candida sp. contamination of preservation fluid.8例保存液受念珠菌属污染患者的肾移植结果
Am J Transplant. 2008 Mar;8(3):697-700. doi: 10.1111/j.1600-6143.2007.02112.x.
2
Infections transmitted from donors to recipients following organ transplantation.器官移植后供体向受体传播的感染。
Natl Med J India. 2005 Jul-Aug;18(4):189-94.
3
Pseudoaneurysm of the iliac artery secondary to Aspergillus infection in two recipients of kidney transplants from the same donor.
同一供体的两名肾移植受者发生曲霉感染继发髂动脉假性动脉瘤。
Am J Kidney Dis. 2003 Feb;41(2):488-92. doi: 10.1053/ajkd.2003.50060.
4
True mycotic arteritis by Candida albicans in 2 kidney transplant recipients from the same donor.来自同一供体的2名肾移植受者发生白色念珠菌所致的真性霉菌性动脉炎。
J Urol. 2000 Apr;163(4):1236-7.
5
Renal artery rupture secondary to pretransplantation Candida contamination of the graft in two different recipients.两名不同受者移植前移植物念珠菌污染继发肾动脉破裂。
Am J Kidney Dis. 1999 Jan;33(1):E3. doi: 10.1016/s0272-6386(99)70292-1.