Persec Zoran, Buković Damir, Persec Jasminka, Sović Tomislav, Ljubanović Danica, Lambasa Smiljka, Radan Mirjana, Babić Ivan
University of Zagreb, Dubrava University Hospital, Department of Urology, Zagreb, Croatia.
Coll Antropol. 2012 Sep;36(3):1041-3.
Tumors that grow within the adrenal medulla are called pheochromocytoma; when located extra-adrenal, they are called paraganglioma. Paraganglioma of the bladder are very rare, with only 180 reported cases. Less than 30 were malignant. We report a case of a 72-years old man with bladder paraganglioma who presented with painless hematuria. Urgent transurethral resection (TUR) was performed. Definitive pathohistological diagnosis was confirmed to imunohistochemical and electron microscopy. Clinical diagnostic showed normal value of epinephrine and norepinehrine in the urine. Scintigraphy of entire body and targeted pictures of pelvis where taken 24, 48 and 72 hours after administration of RI. No loci of pathologic accumulation of 131-I MIBG where found. Computer tomography (CT) of pelvis and abdomen were normal. Considering staging and pathohistological analysis, we treated our patient with TUR and longtime follow-up afterworth.
生长于肾上腺髓质的肿瘤称为嗜铬细胞瘤；位于肾上腺外的则称为副神经节瘤。膀胱副神经节瘤极为罕见，仅有180例报道病例。恶性的不足30例。我们报告一例72岁男性膀胱副神经节瘤患者，表现为无痛性血尿。紧急行经尿道切除术（TUR）。通过免疫组织化学和电子显微镜检查确诊为明确的病理组织学诊断。临床诊断显示尿中肾上腺素和去甲肾上腺素值正常。在注射放射性碘（RI）后24、48和72小时进行全身闪烁扫描及骨盆靶向成像。未发现131-I MIBG病理性聚集部位。骨盆和腹部的计算机断层扫描（CT）结果正常。综合分期及病理组织学分析，我们对患者进行了经尿道切除术并在术后进行长期随访。
