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在全身麻醉下发生失血性休克的荷斯坦奶牛中成功输血。

Successful blood transfusion in a Holstein cow experiencing hemorrhagic shock under general anesthesia.

机构信息

VCA Canada Calgary Animal Referral and Emergency Centre, 7140 12th Street SE, Calgary, Alberta T2H 2Y4 (Mackintosh); Centre Vétérinaire Rive-Sud, 7415 Taschereau Blvd, Brossard, Québec J4Y 1A2 (Rousseau-Blass); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (J. Pang, D. Pang); Faculty of Veterinary Medicine, Université de Montréal, 3200 Rue Sicotte, St-Hyacinthe, Québec J2S 2M2 (D. Pang).

出版信息

Can Vet J. 2023 May;64(5):445-450.

Abstract

A 2-year-old Holstein cow weighing 530 kg at 2 mo gestation was scheduled for a paracostal laparotomy and abomasotomy following diagnosis of a reticular foreign body causing obstruction and abomasal impaction. Hemorrhagic shock occurred during surgery, with a rapid, approximately 60% decrease in arterial blood pressure, and reflex tachycardia with a 2-fold increase in heart rate. Following identification of hemorrhagic shock, arterial blood pressure was supported by reducing the inhalant anesthetic requirement, positive inotropic support (IV dobutamine infusion), and IV fluid therapy. Hypertonic saline was administered IV for initial resuscitation of arterial blood pressure, followed by a whole blood transfusion to replenish red blood cells, support oxygencarrying capacity, and provide intravascular volume to maintain cardiac output and tissue perfusion. A gradual increase in arterial blood pressure and a decrease in heart rate were observed in response to treatment. This case report demonstrates the physiologic compensatory response to hemorrhagic shock and the treatment to stabilize cardiovascular parameters in an anesthetized cow. Key clinical message: This case illustrates the physiological reponses to acute hemorrhage under general anesthesia and the effects of various treatment interventions.

摘要

一只两岁的荷斯坦奶牛,2 个月妊娠期,体重 530 公斤,被诊断为网胃异物导致阻塞和皱胃积食,计划进行肋旁剖腹术和皱胃切开术。手术过程中发生失血性休克,动脉血压迅速下降约 60%,反射性心动过速,心率增加两倍。在确定失血性休克后,通过减少吸入麻醉剂的需求、正性肌力支持(IV 多巴酚丁胺输注)和 IV 液体治疗来维持动脉血压。静脉注射高渗盐水进行初始动脉血压复苏,然后进行全血输血以补充红细胞、支持携氧能力,并提供血管内容量以维持心输出量和组织灌注。治疗后观察到动脉血压逐渐升高,心率下降。本病例报告说明了麻醉牛失血性休克的生理代偿反应以及稳定心血管参数的治疗方法。主要临床信息:本病例说明了全身麻醉下急性出血的生理反应以及各种治疗干预的效果。

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Measuring osmosis and hemolysis of red blood cells.测量红细胞的渗透作用和溶血作用。
Adv Physiol Educ. 2017 Jun 1;41(2):298-305. doi: 10.1152/advan.00083.2016.
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Update on the use of blood and blood products in ruminants.反刍动物血液及血液制品的应用进展。
Vet Clin North Am Food Anim Pract. 2014 Jul;30(2):455-74, vii. doi: 10.1016/j.cvfa.2014.04.001. Epub 2014 May 28.
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Use of blood and blood products.血液及血液制品的使用。
Vet Clin North Am Food Anim Pract. 1999 Nov;15(3):641-62. doi: 10.1016/s0749-0720(15)30168-7.

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