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基质内角膜环段治疗圆锥角膜的结果:五年随访分析。

Outcomes of intrastromal corneal ring segments for treatment of keratoconus: five-year follow-up analysis.

机构信息

Keratoconus Unit, Vissum Instituto Oftalmologico de Alicante, Alicante, Spain.

出版信息

J Cataract Refract Surg. 2013 Aug;39(8):1234-40. doi: 10.1016/j.jcrs.2013.03.019. Epub 2013 Jun 5.

DOI:10.1016/j.jcrs.2013.03.019
PMID:23747207
Abstract

PURPOSE

To report the long-term refractive and optical quality outcomes of patients with intrastromal corneal ring segments (ICRS) to treat keratoconus and to analyze the results according to the patients' age.

SETTING

Vissum Instituto Oftalmologico de Alicante, Alicante, Spain.

DESIGN

Case series.

METHODS

The uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, corneal topography, and aberrometry were evaluated before and after ICRS implantation in eyes with keratoconus. The follow-up was 5 years in all cases.

RESULTS

The study comprised 51 eyes (35 patients; age range 15 to 56 years). After 6 months, the improvement in the UDVA, CDVA, spherical equivalent, and mean keratometry (K) value was statistically significant (P<.05). Five years postoperatively, these parameters remained unchanged (P=.31). Slight regression (0.97 diopter [D]) was observed in the mean K between 6 months and 5 years; the regression was not statistically significant (P=.39). Anterior corneal aberrometric values decreased; however, the changes were not statistically significant (P ≥.10). Linear regression analysis showed no correlation between the age of the patients and the changes observed in the mean K throughout the follow-up (P>.05, r(2) = 0.001).

CONCLUSIONS

Intrastromal corneal ring segment implantation in keratoconus patients provided long-term improvement of the refractive and topographic status. There was no correlation between the amount of individual changes in the mean K reading and patient age.

摘要

目的

报告治疗圆锥角膜的间质内角膜环段(ICRS)患者的长期屈光和光学质量结果,并根据患者年龄进行分析。

地点

西班牙阿利坎特的 Vissum Instituto Oftalmologico de Alicante。

设计

病例系列。

方法

对圆锥角膜患者的 ICRS 植入前后的未矫正远视力(UDVA)、矫正远视力(CDVA)、显性折射、角膜地形图和像差进行评估。所有病例的随访时间均为 5 年。

结果

该研究包括 51 只眼(35 例患者;年龄 15 至 56 岁)。6 个月后,UDVA、CDVA、等效球镜和平均角膜曲率(K)值的改善具有统计学意义(P<.05)。术后 5 年,这些参数保持不变(P=.31)。6 个月至 5 年间,平均 K 值出现轻微回归(0.97 屈光度[D]),但无统计学意义(P=.39)。前角膜像差值降低;然而,变化无统计学意义(P≥.10)。线性回归分析显示,患者年龄与整个随访过程中平均 K 值的变化之间无相关性(P>.05,r²=0.001)。

结论

在圆锥角膜患者中植入间质内角膜环段可长期改善屈光和地形状态。平均 K 值的个体变化量与患者年龄之间无相关性。

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