Macsai M S, Varley G A, Krachmer J H
Department of Ophthalmology, University of Iowa Hospital, Iowa City 52242.
Arch Ophthalmol. 1990 Apr;108(4):534-8. doi: 10.1001/archopht.1990.01070060082054.
A retrospective review of 398 eyes of 199 patients with keratoconus revealed 106 eyes of 53 patients with an association between contact lens wear and the development of keratoconus. The absence of keratoconus at the time of contact lens fitting was confirmed by slit-lamp examination, keratometry readings, and manifest refraction. Keratoconus was diagnosed after a mean of 12.2 years of contact lens wear. This group was compared with patients with sporadic keratoconus with either no history of contact lens wear or a history of contact lens wear after the diagnosis. They were older at the time of diagnosis, had central vs decentered cones, and had a tendency toward flatter corneal curvatures. We believe that these patients suggest that long-term contact lens wear is a factor that can lead to keratoconus.
对199例圆锥角膜患者的398只眼进行回顾性研究发现，53例患者的106只眼中存在隐形眼镜佩戴与圆锥角膜发生之间的关联。在佩戴隐形眼镜时通过裂隙灯检查、角膜曲率测量和显验光确认无圆锥角膜。在平均佩戴隐形眼镜12.2年后诊断为圆锥角膜。将该组患者与无隐形眼镜佩戴史或诊断后有隐形眼镜佩戴史的散发性圆锥角膜患者进行比较。他们在诊断时年龄较大，有中央型与偏心型圆锥，且角膜曲率有较平坦的趋势。我们认为这些患者表明长期佩戴隐形眼镜是导致圆锥角膜的一个因素。
