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电击还是不电击——一个哲学问题,还是应该推荐术中植入式心律转复除颤器测试?

Shock or no shock - a question of philosophy or should intraoperative implantable cardioverter defibrillator testing be recommended?

作者信息

Keyser Andreas, Hilker Michael K, Schmidt Sebastian, von Bary Christian, Zink Wolfgang, Ried Michael, Schmid Christof, Diez Claudius

机构信息

Department of Cardiothoracic Surgery, University Medical Center, Regensburg, Germany.

出版信息

Interact Cardiovasc Thorac Surg. 2013 Mar;16(3):321-5. doi: 10.1093/icvts/ivs479. Epub 2012 Dec 7.

Abstract

OBJECTIVES

Implantation of implantable cardioverter defibrillators (ICDs) in patients with a high risk for life-threatening ventricular arrhythmias is a standard therapy. The development of new ICD leads, shock algorithms, high-energy defibrillators and rapid energy supply has improved the devices. Nevertheless, the discussion regarding 'shock or no shock' to test the system intraoperatively has not silenced yet.

METHODS

In this study, all 718 patients (60.0 ± 14.2 years old, 570 male) who were treated with a first ICD at our institution since 2005 were analysed. The indication for implantation was primarily prophylactic in 511 patients (71.3%). Underlying diseases included ischaemic cardiomyopathy (358 patients, 50%), dilated cardiomyopathy (270 patients, 37.7%) and others (12.3%). Mean ejection fraction was 27.4 ± 11.8%. Intraoperative ventricular fibrillation was induced with a T-wave shock or burst stimulation. The primary end-point was failing the initial intraoperative testing.

RESULTS

During the initial testing, 28 patients (3.9%) had a defibrillation threshold (DFT) >21 J. The mean age of these patients was 51 ± 14 years, ranging from 22 to 71 years, 20 were male, and the ejection fraction was 23.8 ± 11.8%. The indication for ICD implantation was prophylactic in 13 patients. Twenty-one of the 28 patients suffered from dilated cardiomyopathy, whereas seven patients had ischaemic cardiomyopathy. Twenty-four ICDs were implanted on the left side and four on the right side. None of the patients had been treated with amiodarone at the time of implantation. All patients achieved a sufficient DFT ≤ 21 J by changing the ICD leads, device repositioning and/or optimizing the shock configuration.

CONCLUSIONS

The standard of care intraoperative ICD testing remains necessary.

摘要

目的

对于有发生危及生命的室性心律失常高风险的患者,植入植入式心律转复除颤器(ICD)是一种标准治疗方法。新型ICD导线、电击算法、高能除颤器和快速能量供应的发展改进了这些设备。然而,关于术中测试系统时“电击还是不电击”的讨论仍未平息。

方法

本研究分析了自2005年以来在我们机构接受首次ICD治疗的所有718例患者(年龄60.0±14.2岁,男性570例)。植入的主要适应证为预防性,共511例患者(71.3%)。基础疾病包括缺血性心肌病(358例患者,50%)、扩张型心肌病(270例患者,37.7%)及其他(12.3%)。平均射血分数为27.4±11.8%。术中通过T波电击或短阵刺激诱发室颤。主要终点是初次术中测试失败。

结果

在初次测试期间,28例患者(3.9%)的除颤阈值(DFT)>21J。这些患者的平均年龄为51±14岁,年龄范围为22至71岁,男性20例,射血分数为23.8±11.8%。ICD植入的适应证为预防性的有13例患者。28例患者中有21例患有扩张型心肌病,7例患有缺血性心肌病。24例ICD植入在左侧,4例植入在右侧。植入时所有患者均未接受胺碘酮治疗。所有患者通过更换ICD导线、调整设备位置和/或优化电击配置均实现了足够的DFT≤21J。

结论

术中ICD测试的护理标准仍然是必要的。

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