Bhunu C P, Mushayabasa S
Department of Mathematics, University of Zimbabwe, Box MP 167, Mount Pleasant, Harare, Zimbabwe.
Theory Biosci. 2013 Jun;132(2):83-92. doi: 10.1007/s12064-012-0171-2. Epub 2012 Dec 6.
Drug misuse (injecting drug users-IDU) has been recognized to have a significant effect on the spread of HIV/AIDS epidemic. A deterministic model to assess the contribution of drug misuse and sex in the spread of HIV/AIDS is investigated. The threshold parameters of the model are determined and stabilities are analysed. Analysis of the reproduction number has shown that increase in drug misuse results in an increase in HIV infections. Furthermore, numerical simulations of the model show that drug misuse enhances HIV transmission and progression to AIDS. Thus, in a population with intravenous drug users, advocating for safe sex alone will not be enough to control the HIV/AIDS epidemic.
药物滥用(注射吸毒者)已被认为对艾滋病毒/艾滋病的传播有重大影响。研究了一个确定性模型,以评估药物滥用和性行为在艾滋病毒/艾滋病传播中的作用。确定了该模型的阈值参数并分析了稳定性。对繁殖数的分析表明,药物滥用的增加导致艾滋病毒感染的增加。此外,该模型的数值模拟表明,药物滥用会增强艾滋病毒的传播并加速发展为艾滋病。因此,在有静脉注射吸毒者的人群中,仅倡导安全性行为不足以控制艾滋病毒/艾滋病的流行。