衰老大脑的神经增强：恢复老年受试者的技能获取。
Neuroenhancement of the aging brain: restoring skill acquisition in old subjects.
机构信息
Brain Imaging and Neurostimulation Laboratory, Department of Neurology, University Medical Center Hamburg-Eppendorf, Germany.
出版信息
Ann Neurol. 2013 Jan;73(1):10-5. doi: 10.1002/ana.23761. Epub 2012 Dec 7.
Abstract
OBJECTIVE
Decline in cognitive functions, including impaired acquisition of novel skills, is a feature of older age that impacts activities of daily living, independence, and integration in modern societies.
METHODS
We tested whether the acquisition of a complex motor skill can be enhanced in old subjects by the application of transcranial direct current stimulation (tDCS) to the motor cortex.
RESULTS
The main finding was that old participants experienced substantial improvements when training was applied concurrent with tDCS, with effects lasting for at least 24 hours.
INTERPRETATION
These results suggest noninvasive brain stimulation as a promising and safe tool to potentially assist functional independence of aged individuals in daily life.
摘要
目的
认知功能下降，包括新技能习得受损，是老年的一个特征，会影响日常生活活动、独立性和现代社会的融入。
方法
我们测试了经颅直流电刺激（tDCS）应用于运动皮层是否可以增强老年受试者对复杂运动技能的习得。
结果
主要发现是，当训练与 tDCS 同时应用时，老年参与者经历了实质性的改善，效果至少持续 24 小时。
结论
这些结果表明，非侵入性脑刺激是一种有前途的、安全的工具，可以潜在地帮助老年人在日常生活中保持功能独立性。
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