Galloway Sarah K, Baker Megan, Giglio Pierre, Chin Steve, Madan Alok, Malcolm Robert, Serber Eva R, Wedin Sharlene, Balliet Wendy, Borckardt Jeffrey
Division of Biobehavioral Medicine, Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina, 67 President Street, 1-South, Charleston, SC 29425, USA.
Pain Res Treat. 2012;2012:851276. doi: 10.1155/2012/851276. Epub 2012 Nov 21.
Breast cancer is a leading cancer diagnosis among women worldwide, with more than 210,000 new cases and 40,000 deaths per year in the United States. Pain, anxiety, and depression can be significant factors during the course of breast cancer. Pain is a complex experience with sensory, affective, and cognitive dimensions. While depression and anxiety symptoms are relatively common among breast cancer patients, little is known about the relation between these psychiatric factors and distinct components of the pain experience. In the present study 60 females presenting to an NCI-designated Cancer Center with newly diagnosed breast cancer completed the Center for Epidemiological Studies 10-item Depression Scale, the State Instrument of the Spielberger State-Trait Anxiety Inventory, and the McGill Pain Questionnaire. Findings indicate that anxiety and depression are common among newly diagnosed breast cancer patients; furthermore, patients experience an appreciable amount of pain even before oncologic treatment starts. State anxiety serves as a predictor of the sensory dimension of the pain experience, whereas depression serves as a predictor of the affective dimension of the pain experience.
乳腺癌是全球女性中最常见的癌症诊断类型，在美国每年有超过21万新发病例和4万例死亡。疼痛、焦虑和抑郁在乳腺癌病程中可能是重要因素。疼痛是一种具有感觉、情感和认知维度的复杂体验。虽然抑郁和焦虑症状在乳腺癌患者中相对常见，但对于这些精神因素与疼痛体验的不同组成部分之间的关系却知之甚少。在本研究中，60名新诊断为乳腺癌并前往美国国立癌症研究所指定癌症中心就诊的女性完成了流行病学研究中心10项抑郁量表、斯皮尔伯格状态-特质焦虑量表的状态量表以及麦吉尔疼痛问卷。研究结果表明，焦虑和抑郁在新诊断的乳腺癌患者中很常见；此外，患者在肿瘤治疗开始前就经历了相当程度的疼痛。状态焦虑是疼痛体验感觉维度的预测指标，而抑郁是疼痛体验情感维度的预测指标。
