Anderson W A, Bruni J E, Kaufmann A
Department of Anatomy, University of Manitoba, Winnipeg, Canada.
Brain Res Bull. 1990 Feb;24(2):191-200. doi: 10.1016/0361-9230(90)90205-e.
Neurons projecting to the supraoptic nucleus (SON) have been identified following stereotaxic injections of either horseradish peroxidase or fast blue into the SON region of adult rats. The subfornical organ, median preoptic nucleus, organum vasculosum of the lamina terminalis and medial septal nucleus were the source of the largest numbers of supraoptic-projecting neurons. Several smaller projections also originate from the ipsilateral locus coeruleus, preoptic area, lateral parolfactorial area, dorsomedial nucleus of the hypothalamus, lateral parabrachial nucleus and ventrolateral medulla. Several other areas appeared to project only to the region immediately dorsal to the SON: lateral septal nucleus, diagonal band of Broca, ventral tegmental nucleus, and the supramamillary nucleus. These areas may influence SON neurosecretory function by way of interneurons found immediately dorsal to SON. Additional areas were identified with retrograde fluorescent label only, and these projected to the area immediately dorsal to SON and/or to SON itself.
在成年大鼠的视上核（SON）区域立体定向注射辣根过氧化物酶或快蓝后，已鉴定出投射到视上核的神经元。穹窿下器官、视前正中核、终板血管器和内侧隔核是投射到视上核的神经元数量最多的来源。几个较小的投射也起源于同侧蓝斑、视前区、外侧旁嗅觉区、下丘脑背内侧核、外侧臂旁核和延髓腹外侧。其他几个区域似乎仅投射到视上核背侧紧邻的区域：外侧隔核、布罗卡斜带、腹侧被盖核和乳头体上核。这些区域可能通过视上核背侧紧邻处发现的中间神经元影响视上核的神经分泌功能。仅通过逆行荧光标记鉴定出了其他区域，这些区域投射到视上核背侧紧邻的区域和/或视上核本身。
