Miselis R R, Shapiro R E, Hand P J
Science. 1979 Sep 7;205(4410):1022-5. doi: 10.1126/science.472723.
The subfornical organ, a circumventricular structure of the central nervous system, has efferent neural projections to sites within the brain known to be involved in drinking behavior and secretion of antidiuretic hormone. By using anterograde tracing techniques, it is shown that the subfornical organ projects to the nucleus medians of the medial preoptic area, to the organum vasculosum of the lamina terminalis, and to the supraoptic nuclei bilaterally. Its efferent connectivity is confirmed by retrograde transport of horseradish peroxidase. The organum vasculosum of the lamina terminalis, another circumventricular organ and a suspected receptor site for angiotensin II, is involved in the circuitry of the subfornical organ and also has an efferent projection to the supraoptic nuclei.
穹窿下器是中枢神经系统的一种室周结构，它向脑内已知参与饮水行为和抗利尿激素分泌的部位发出传出神经投射。通过运用顺行追踪技术，发现穹窿下器投射到内侧视前区的正中核、终板血管器以及双侧的视上核。辣根过氧化物酶的逆行运输证实了其传出连接。终板血管器是另一种室周器官，也是血管紧张素II的疑似受体部位，它参与穹窿下器的神经回路，并且也向视上核发出传出投射。
