Demirkol Sait, Unlü Murat, Arslan Zekeriya, Baysan Oben, Balta Sevket, Kurt Ibrahim Halil, Küçük Uğur, Celik Turgay
Department of Cardiology, Gülhane Military Medical Academy, Ankara-Turkey.
Anadolu Kardiyol Derg. 2013 Mar;13(2):103-7. doi: 10.5152/akd.2013.032. Epub 2012 Dec 7.
The objective of our study is to determine the mean values of right ventricular (RV) dP/dt and to compare it with other right ventricular function parameters by echocardiography.
This observational study consisted of 112 healthy subjects who had trivial tricuspid regurgitation. Full echocardiographic examination was performed. RV systolic function was assessed by using myocardial performance index (RV MPI), tricuspid annular plane systolic excursion (TAPSE), myocardial acceleration during isovolumic contraction (RV IVA), RV fractional area change (RV FAC), tissue Doppler-derived tricuspid lateral annular systolic velocity (Tri S`) and RV dP/dt (dP/dt). Pearson correlation test was used in examining the correlation between parameters. Differences between correlations were compared with Fisher's z transformation.
The mean of RV dP/dt (0.5-2) was 1016±421 mmHg/s (95% CI=891-1142) and the mean of RV dP/dt (1-2) was 1524±573 mmHg/s (95% CI=1354-1694). RV pulse Doppler MPI and RV tissue Doppler imaging MPI were negatively correlated with RV dP/dt (0.5-2) (r=-0.482 and r=-0.504, p<0.01). Tri S' was positively correlated with RV dP/dt (0.5-2) (r=0.667, p<0.01) and with the RV dP/dt (1-2) (r=0.312, p<0.05). TAPSE was positively correlated with RV dP/dt (0.5-2) (r=0.585, p<0.01) and with the RV dP/dt (1-2) (r=0.323, p<0.05). RV IVA was positively correlated with RV dP/dt (0.5-2) (r=0.512, p<0.01). FAC (%) was not correlated with both RV dP/dt (0.5-2) and RV dP/dt (1-2).
The results of our study were as follows: 1) we described the mean of RV dP/dt (0.5-2) and RV dP/dt (1-2) in healthy population; 2) the correlation between dP/dt (0.5-2) and RV function parameters was better than between dP/dt (1-2) and RV function parameters.
本研究的目的是通过超声心动图测定右心室（RV）dp/dt的平均值，并将其与其他右心室功能参数进行比较。
本观察性研究纳入了112例有轻微三尖瓣反流的健康受试者。进行了完整的超声心动图检查。采用心肌性能指数（RV MPI）、三尖瓣环平面收缩期位移（TAPSE）、等容收缩期心肌加速度（RV IVA）、RV面积变化分数（RV FAC）、组织多普勒衍生的三尖瓣侧环收缩期速度（Tri S`）和RV dp/dt（dp/dt）评估RV收缩功能。采用Pearson相关检验来检验参数之间的相关性。相关性之间的差异采用Fisher z变换进行比较。
RV dp/dt（0.5 - 2）的平均值为1016±421 mmHg/s（95%CI = 891 - 1142），RV dp/dt（1 - 2）的平均值为1524±573 mmHg/s（95%CI = 1354 - 1694）。RV脉冲多普勒MPI和RV组织多普勒成像MPI与RV dp/dt（0.5 - 2）呈负相关（r = -0.482和r = -0.504，p<0.01）。Tri S`与RV dp/dt（0.5 - 2）呈正相关（r = 0.667，p<0.01），与RV dp/dt（1 - 2）呈正相关（r = 0.312，p<0.05）。TAPSE与RV dp/dt（0.5 - 2）呈正相关（r = 0.585，p<0.01），与RV dp/dt（1 - 2）呈正相关（r = 0.323，p<0.05）。RV IVA与RV dp/dt（0.5 - 2）呈正相关（r = 0.512，p<0.01）。FAC（%）与RV dp/dt（0.5 - 2）和RV dp/dt（1 - 2）均无相关性。
我们的研究结果如下：1）我们描述了健康人群中RV dp/dt（0.5 - 2）和RV dp/dt（1 - 2）的平均值；2）dp/dt（0.5 - 2）与RV功能参数之间的相关性优于dp/dt（1 - 2）与RV功能参数之间的相关性。
