Angelini E, Marinaro C, Carrozzo A M, Bianchi L, Delogu A, Giannello G, Nini G
Istituto di Dermatologia e Venereologia, Università degli Studi di Roma Tor Vergata, Rome, Italy.
Contact Dermatitis. 1993 Mar;28(3):146-8. doi: 10.1111/j.1600-0536.1993.tb03375.x.
We describe the use of gas chromatography with mass spectrometry (GC-MS) in the investigation of a case of allergic contact dermatitis of the lip margins caused by a lip liner. Patch testing identified sensitization to para-tertiary-butylphenol-formaldehyde resin (PTBP-FR), a resin glue frequently used in leather work but rarely found in cosmetics. Investigation specified the para-tertiary-butylphenol (PTBP) component of the resin as the hapten responsible for the allergic contact dermatitis, as well as for associated depigmentation.
我们描述了使用气相色谱-质谱联用（GC-MS）技术对一例由唇线笔引起的唇缘过敏性接触性皮炎病例进行调查的情况。斑贴试验确定对对叔丁基苯酚甲醛树脂（PTBP-FR）过敏，该树脂胶常用于皮革制品，在化妆品中很少见。调查表明，该树脂中的对叔丁基苯酚（PTBP）成分是导致过敏性接触性皮炎以及相关色素脱失的半抗原。
