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主动脉疾病的生物标志物。

Biomarkers of aortic diseases.

机构信息

Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.

出版信息

Am Heart J. 2013 Jan;165(1):15-25. doi: 10.1016/j.ahj.2012.10.006. Epub 2012 Nov 20.

Abstract

The development of diagnostic biomarkers of acute cardiovascular disease remains an important topic of interest given potential use to aid in early diagnosis. Cardiac biomarkers of ischemia and heart failure have already proven to be clinically useful. Biomarkers of aortic diseases are also needed, especially for life-threatening conditions such as aortic dissection. In this review, we discuss the present status of the development of biomarkers of aortic diseases. Although aortic dissection has been most vigorously pursued, there has also been notable recent progress in biomarkers of aneurysms and inflammatory aortic disease.

摘要

鉴于潜在的辅助早期诊断的用途,急性心血管疾病的诊断生物标志物的开发仍然是一个重要的研究课题。缺血和心力衰竭的心脏生物标志物已经被证明具有临床应用价值。还需要主动脉疾病的生物标志物,特别是对于主动脉夹层等危及生命的情况。在这篇综述中,我们讨论了主动脉疾病生物标志物的发展现状。虽然主动脉夹层的研究最为活跃,但在动脉瘤和炎症性主动脉疾病的生物标志物方面也取得了显著的近期进展。

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