Converging on a mechanism for choline degradation.
作者信息
Thibodeaux Christopher J, van der Donk Wilfred A
机构信息
Institute for Genomic Biology, University of Illinois, Urbana, IL 61801, USA.
出版信息
Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21184-5. doi: 10.1073/pnas.1219534110. Epub 2012 Dec 14.
Abstract
摘要
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本文引用的文献
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Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme.胆碱向三甲胺的微生物转化需要甘氨酰基自由基酶。
Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21307-12. doi: 10.1073/pnas.1215689109. Epub 2012 Nov 14.
2
Glycerol dehydratation by the B12-independent enzyme may not involve the migration of a hydroxyl group: a computational study.B12 非依赖型酶的甘油脱水作用可能不涉及羟基迁移：一项计算研究。
J Phys Chem B. 2012 Jun 21;116(24):7076-87. doi: 10.1021/jp301165b. Epub 2012 Jun 8.
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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.肠道菌群对磷脂酰胆碱的代谢作用促进了心血管疾病的发生。
Nature. 2011 Apr 7;472(7341):57-63. doi: 10.1038/nature09922.
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Crystal structures of ethanolamine ammonia-lyase complexed with coenzyme B12 analogs and substrates.乙醇胺氨裂解酶与辅酶 B12 类似物和底物复合物的晶体结构。
J Biol Chem. 2010 Aug 20;285(34):26484-93. doi: 10.1074/jbc.M110.125112. Epub 2010 Jun 1.
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Ethanolamine utilization in bacterial pathogens: roles and regulation.乙醇胺在细菌病原体中的利用：作用与调控。
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Modeling the reactions catalyzed by coenzyme B12-dependent enzymes.模拟钴胺素 B12 依赖性酶催化的反应。
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