Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany.
Cancer Biomark. 2012;11(6):253-7. doi: 10.3233/CBM-2012-0274.
MicroRNAs (miRNAs) are a fairly novel class of 17- to 23-nucleotide (nt), short, non-coding RNA molecules that have revolutionized our understanding of gene regulation and opened new possibilities in the future of gene therapy. Here, we review the potential role of miRNAs in non-melanoma skin cancer (NMSC) and summarize the current studies available in this new aspect of NMSC research.
MicroRNAs (miRNAs) 是一类相对较新的 17 到 23 个核苷酸 (nt) 的短非编码 RNA 分子，它们彻底改变了我们对基因调控的理解，并为基因治疗的未来开辟了新的可能性。在这里，我们回顾了 miRNAs 在非黑色素瘤皮肤癌 (NMSC) 中的潜在作用，并总结了目前在 NMSC 研究这一新领域中的相关研究。
