Garnlund D J, Levine P H, Fuccillo D A
J Clin Microbiol. 1979 Nov;10(5):747-51. doi: 10.1128/jcm.10.5.747-751.1979.
Antibody to Epstein-Barr virus-induced early antigen could be measured in sera using enzyme-linked antibody. The sensitivity of this assay was comparable to that of the indirect immunofluorescent technique. Measurement of early antigen was accomplished on a producer cell line which was specifically treated to block late gene expression. It is now possible to measure Epstein-Barr virus-induced early antigen and viral capsid antigen antibodies by using the same cell line.
可使用酶联抗体检测血清中针对爱泼斯坦-巴尔病毒诱导早期抗原的抗体。该检测方法的灵敏度与间接免疫荧光技术相当。早期抗原的检测是在一个经过特殊处理以阻断晚期基因表达的生产细胞系上完成的。现在利用同一细胞系就能够检测爱泼斯坦-巴尔病毒诱导的早期抗原抗体和病毒衣壳抗原抗体。