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美国哮喘住院率和死亡率的季节性趋势。

Seasonal trends in US asthma hospitalizations and mortality.

作者信息

Weiss K B

机构信息

Department of Health Care Sciences, George Washington University Medical Center, Washington, DC 20037.

出版信息

JAMA. 1990 May 2;263(17):2323-8.

PMID:2325233
Abstract

Asthma morbidity is known to exhibit seasonal periodicity. Yet the relationship between trends in morbidity vs mortality is not known. This report describes and compares the seasonal variation in asthma hospitalizations and mortality in the US population. During 1982 through 1986, both mortality and hospitalizations demonstrated periodic seasonal trends that were age specific and did not differ by sex, race, or region. For persons aged 5 through 34 years, hospitalizations peaked in September through November, whereas mortality trends peaked in June through August. A disproportionate number of the summer deaths in this age group occurred out of the hospital. For individuals 65 years old or older, both asthma hospitalizations and mortality demonstrated increases during December through February. The results of this study demonstrate age-specific seasonal variations in the clinical expression of asthma. Perhaps the treatment and prevention of asthma hospitalizations and mortality might be improved through further understanding of these trends.

摘要

已知哮喘发病率呈现季节性周期变化。然而,发病率与死亡率之间的关系尚不清楚。本报告描述并比较了美国人群中哮喘住院率和死亡率的季节性变化。在1982年至1986年期间,死亡率和住院率均呈现出特定年龄的周期性季节性趋势,且在性别、种族或地区方面没有差异。对于5至34岁的人群,住院率在9月至11月达到峰值,而死亡率趋势在6月至8月达到峰值。该年龄组夏季死亡病例中,有相当一部分发生在院外。对于65岁及以上的个体,哮喘住院率和死亡率在12月至2月期间均有所上升。本研究结果表明哮喘临床表现存在特定年龄的季节性变化。或许通过进一步了解这些趋势,哮喘住院率和死亡率的治疗与预防可能会得到改善。

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