太赫兹成像在癌症诊断中的应用潜力：迄今为止的研究综述。
The potential of terahertz imaging for cancer diagnosis: A review of investigations to date.
机构信息
Department of Electronic & Computer Engineering, Hong Kong University of Science and Technology, Hong Kong;
出版信息
Quant Imaging Med Surg. 2012 Mar;2(1):33-45. doi: 10.3978/j.issn.2223-4292.2012.01.04.
The terahertz region lies between the microwave and infrared regions of the electromagnetic spectrum such that it is strongly attenuated by water and very sensitive to water content. Terahertz radiation has very low photon energy and thus it does not pose any ionization hazard for biological tissues. Because of these characteristic properties, there has been an increasing interest in terahertz imaging and spectroscopy for biological applications within the last few years and more and more terahertz spectra are being reported, including spectroscopic studies of cancer. The presence of cancer often causes increased blood supply to affected tissues and a local increase in tissue water content may be observed: this acts as a natural contrast mechanism for terahertz imaging of cancer. Furthermore the structural changes that occur in affected tissues have also been shown to contribute to terahertz image contrast. This paper introduces terahertz technology and provides a short review of recent advances in terahertz imaging and spectroscopy techniques. In particular investigations relating to the potential of terahertz imaging and spectroscopy for cancer diagnosis will be highlighted.
太赫兹波段位于电磁频谱的微波和红外区域之间，因此它被水强烈衰减，对含水量非常敏感。太赫兹辐射的光子能量非常低，因此不会对生物组织造成任何电离危险。由于这些特性，太赫兹成像和光谱学在过去几年中引起了人们对生物应用的越来越多的兴趣，越来越多的太赫兹光谱被报道，包括癌症的光谱研究。癌症的存在通常会导致受影响组织的血液供应增加，并且可能观察到组织含水量的局部增加：这是太赫兹成像癌症的自然对比机制。此外，受影响组织中发生的结构变化也被证明有助于太赫兹图像对比。本文介绍了太赫兹技术，并对太赫兹成像和光谱技术的最新进展进行了简要回顾。特别是，将重点介绍太赫兹成像和光谱技术在癌症诊断方面的应用潜力的相关研究。
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