Department of Ophthalmology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, P. R. China.
Ophthalmology. 2013 Apr;120(4):703-8. doi: 10.1016/j.ophtha.2012.09.034. Epub 2012 Dec 20.
To investigate anterior segment parameters in normal Chinese subjects and study factors influencing these parameters, such as age, gender, and laterality.
A prospective observational case series.
A total of 291 normal subjects (582 eyes) were included.
The anterior segment data were determined with a dual Scheimpflug analyzer.
The corneal thinnest-point thickness (CTPT), corneal thinnest-point distribution (CTPD), central corneal thickness (CCT), corneal thickness (CT) in the central 10 mm diameter, pupil diameter (PD), pupil center distribution (PCD), anterior chamber depth (ACD), and anterior chamber volume (ACV, 8-mm diameter) were measured.
The mean distance between the thinnest point and the corneal vertex was 0.70 ± 0.32 mm in the right eyes and 0.42 ± 0.25 mm in the left eyes; the thinnest point was located in the inferior temporal region in 71.1% of the right eyes and 55% of the left eyes. The CCT values were thicker than the CTPT values, and they were positively correlated (right eyes r = 0.994, P<0.001; left eyes r = 0.997, P<0.001). The distance between the pupillary center and the corneal vertex was approximately 0.39 ± 0.27 mm in the right eyes and 0.37 ± 0.24 mm in the left eyes. Furthermore, the percentage of pupillary centers located in the superior regions was 72.2% in the right eyes and 73.5% in the left eyes. Age was negatively correlated with the peripheral CT (7-10 mm diameter), PD, ACD, and ACV of both eyes and the mid-peripheral CT (4-7 mm diameter) of the right eye. Laterality correlated with CTPT (P<0.001) and PD (P<0.001), whereas gender correlated with ACD (P<0.001) and ACV (P = 0.009).
The majority of the thinnest corneal points were located in the inferior temporal quadrant, and the pupillary center was located in the superior region of the cornea; both differed substantially from the corneal vertex. The CT increased gradually from the center to the periphery. Age, gender, and laterality correlated with some indexes.
调查正常中国人群的眼前节参数，并研究影响这些参数的因素，如年龄、性别和侧别。
前瞻性观察性病例系列。
共纳入 291 名正常受试者（582 只眼）。
使用双 Scheimpflug 分析仪确定眼前节数据。
角膜最薄点厚度（CTPT）、角膜最薄点分布（CTPD）、中央角膜厚度（CCT）、中央 10mm 直径角膜厚度（CT）、瞳孔直径（PD）、瞳孔中心分布（PCD）、前房深度（ACD）和前房容积（ACV，8mm 直径）。
右眼最薄点与角膜顶点之间的平均距离为 0.70±0.32mm，左眼为 0.42±0.25mm；右眼最薄点位于下颞象限的占 71.1%，左眼为 55%。CCT 值比 CTPT 值厚，且两者呈正相关（右眼 r=0.994，P<0.001；左眼 r=0.997，P<0.001）。右眼瞳孔中心与角膜顶点之间的距离约为 0.39±0.27mm，左眼为 0.37±0.24mm。此外，右眼瞳孔中心位于上象限的百分比为 72.2%，左眼为 73.5%。年龄与双眼周边 CT（7-10mm 直径）、PD、ACD 和 ACV 以及右眼中周边 CT（4-7mm 直径）呈负相关。侧别与 CTPT（P<0.001）和 PD（P<0.001）相关，而性别与 ACD（P<0.001）和 ACV（P=0.009）相关。
大多数最薄角膜点位于下颞象限，瞳孔中心位于角膜的上象限；这两个位置都与角膜顶点有很大的不同。CT 从中心向周边逐渐增加。年龄、性别和侧别与某些指标相关。
