National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China.
Antimicrob Agents Chemother. 2013 Mar;57(3):1521-3. doi: 10.1128/AAC.02060-12. Epub 2012 Dec 21.
Macrolide resistance rates of Mycoplasma pneumoniae in the Beijing population were as high as 68.9%, 90.0%, 98.4%, 95.4%, and 97.0% in the years 2008 to 2012, respectively. Common macrolide-resistant mobile genetic elements were not detected with any isolate. These macrolide-resistant isolates came from multiple clones rather than the same clone. No massive aggregation of a particular clone was found in a specific period.
2008 年至 2012 年,北京地区肺炎支原体大环内酯类耐药率分别高达 68.9%、90.0%、98.4%、95.4%和 97.0%。未检测到任何分离株携带常见的大环内酯类耐药移动遗传元件。这些耐药分离株来自多个克隆体,而非同一个克隆体。在特定时期,未发现特定克隆体的大规模聚集。