缺血性卒中中的代谢综合征：一项病例对照研究。
Metabolic syndrome in ischemic stroke: A case control study.
作者信息
Ashtari Fereshteh, Salari Mehri, Aminoroaya Ashraf, Deljoo Behnaz Khademi, Moeini Mina
机构信息
Associate Professor, Department of Neurology, School of Medicine and Isfahan Neuroscience Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Res Med Sci. 2012 Feb;17(2):167-70.
INTRODUCTION
The metabolic syndrome has known as an independent risk factor of stroke. The occurrence of this syndrome is due to genetic factors and lifestyle. This study was performed on the frequency of metabolic syndrome prevalence in ischemic stroke patients compare to control.
MATERIALS AND METHODS
one hundred ischemic stroke patients and 100 controls (with the same age and sex) were evaluated for this study.
RESULT
62% of patient and 34% of controls had metabolic syndrome criteria according to National Cholesterol Education Program (NCEP) {OR: 3.2; 95% CI (1.9-9.7), P=0.001} Prevalence of metabolic syndrome in women was more than men (52% vs. 44%) {OR: 0.72; 95% CI (0.4, 1.3)}. Beside of metabolic syndrome, prevalence of metabolic syndrome components was significantly higher in stroke patients compare to controls.
CONCLUSION
metabolic syndrome prevalence are more common in stroke patients compare to controls, but it should be noticed that the controls are in a risk of future stroke so they need special treatment to prevent it.
引言
代谢综合征被认为是中风的一个独立危险因素。该综合征的发生归因于遗传因素和生活方式。本研究旨在比较缺血性中风患者与对照组中代谢综合征的患病率。
材料与方法
本研究评估了100例缺血性中风患者和100名对照组（年龄和性别相同）。
结果
根据美国国家胆固醇教育计划（NCEP），62%的患者和34%的对照组符合代谢综合征标准{比值比：3.2；95%置信区间（1.9 - 9.7），P = 0.001}。女性代谢综合征的患病率高于男性（52%对44%）{比值比：0.72；95%置信区间（0.4，1.3）}。除代谢综合征外，中风患者中代谢综合征各组分的患病率显著高于对照组。
结论
与对照组相比，中风患者中代谢综合征的患病率更高，但应注意的是，对照组存在未来发生中风的风险，因此他们需要特殊治疗以预防中风。
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