Department of Surgery of Dou-liou Branch, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan.
J Formos Med Assoc. 2012 Dec;111(12):719-23. doi: 10.1016/j.jfma.2012.07.012. Epub 2012 Dec 14.
Riedel's thyroiditis, known as invasive fibrous thyroiditis, is a very rare form of chronic thyroiditis. It is hard to make the diagnosis without surgical biopsy. We present a case of Riedel's thyroiditis in a 52-year-old female with past history of Hashimoto's thyroiditis. She suffered from bilateral neck pain, which radiated to both lower jaws. The erythrocyte sedimentation rate was 125 mm/hour. Subacute thyroiditis superimposed on Hashimoto's thyroiditis was diagnosed and treated with steroid. However the response was poor and she had a history of severe peptic ulcer. To avoid inducing the peptic ulcer by steroid, she received bilateral subtotal thyroidectomy. During surgery, the thyroid had severe adhesion to surrounding soft tissue and the pathology showed Riedel's thyroiditis. The neck pain improved after thyroidectomy. Tamoxifen has been given for 8 months and the size of remnant thyroid decreased to 8 mm. We concluded that combined thyroidectomy and tamoxifen successfully cured a patient with Riedel's thyroiditis.
Riedel 甲状腺炎,又称侵袭性纤维性甲状腺炎,是一种非常罕见的慢性甲状腺炎。如果没有手术活检,很难做出诊断。我们报告一例 52 岁女性的 Riedel 甲状腺炎病例,该患者既往有桥本甲状腺炎病史。她双侧颈部疼痛,放射至双侧下颌。红细胞沉降率为 125mm/小时。诊断为亚急性甲状腺炎合并桥本甲状腺炎,给予类固醇治疗。但反应不佳,且有严重消化性溃疡病史。为避免类固醇引起消化性溃疡,患者接受了双侧甲状腺次全切除术。术中发现甲状腺与周围软组织严重粘连,病理检查显示为 Riedel 甲状腺炎。甲状腺切除术后颈部疼痛缓解。患者已服用他莫昔芬 8 个月,残余甲状腺大小缩小至 8mm。我们得出结论,甲状腺切除术联合他莫昔芬成功治愈了一例 Riedel 甲状腺炎患者。