Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan.
Br J Ophthalmol. 2013 Aug;97(8):968-75. doi: 10.1136/bjophthalmol-2012-302047. Epub 2012 Dec 25.
To compare postoperative visual acuity, higher-order aberrations (HOAs) and corneal asphericity after femtosecond lenticule extraction (FLEx) and after wavefront-guided laser-assisted in situ keratomileusis (wfg-LASIK) in myopic eyes.
We examined 43 eyes of 23 patients undergoing FLEx and 34 eyes of 19 patients undergoing wfg-LASIK to correct myopia. Ocular HOAs were measured by Hartmann-Shack aberrometry and corneal asphericity was measured by a rotating Scheimpflug imaging system before and 3 months after surgery.
There was no statistically significant difference in uncorrected (p=0.66 Mann-Whitney U-test) or corrected distance visual acuity (p=0.14) after two surgical procedures. For a 6-mm pupil, the changes in fourth-order aberrations after FLEx were statistically significantly less than those after wfg-LASIK (p<0.001). On the other hand, there were no statistically significant differences in the changes in third-order aberrations (p=0.24) and total HOAs (p=0.13). Similar results were obtained for a 4-mm pupil. The positive changes in the Q value after FLEx were statistically significantly less than those after wfg-LASIK (p=0.001).
In myopic eyes, FLEx induces significantly fewer ocular fourth-order aberrations than wfg-LASIK, possibly because it causes less oblation in the corneal shape, but there was no statistically significant difference in visual acuity or in the induction of third-order aberrations and total HOAs. It is suggested that FLEx is essentially equivalent to wfg-LASIK in terms of visual acuity and total HOA induction, although the characteristics of HOA induction are different.
比较飞秒激光小切口透镜取出术(FLEx)与波前引导准分子激光原位角膜磨镶术(wfg-LASIK)治疗近视术后的视力、高阶像差(HOAs)和角膜非球面性。
本研究纳入了 23 例(43 眼)接受 FLEx 手术和 19 例(34 眼)接受 wfg-LASIK 手术的近视患者。术前和术后 3 个月,使用哈特曼-夏克(Hartmann-Shack)波前像差仪测量眼的 HOAs,使用旋转式Scheimpflug 成像系统测量角膜非球面性。
两种手术方式术后的未矫正视力(p=0.66,Mann-Whitney U 检验)和矫正视力(p=0.14)均无统计学差异。对于 6mm 瞳孔,FLEx 术后第四阶像差的变化明显小于 wfg-LASIK(p<0.001)。另一方面,第三阶像差(p=0.24)和总 HOAs(p=0.13)的变化无统计学差异。对于 4mm 瞳孔,也得到了相似的结果。FLEx 术后 Q 值的正性变化明显小于 wfg-LASIK(p=0.001)。
在近视眼中,FLEx 引起的眼高阶像差明显少于 wfg-LASIK,可能是因为它对角膜形状的切削较少,但视力和第三阶像差及总 HOAs的诱导无统计学差异。FLEx 在视力和总 HOAs 的诱导方面与 wfg-LASIK 基本等效,尽管像差诱导的特征不同。