Williams P L, Moffat A C, King L J
J Chromatogr. 1979 Dec 30;186:595-603. doi: 10.1016/s0021-9673(00)95280-4.
A high-performance liquid chromatography-radioimmunoassay method for the measurement of cannabinoids in urine is described. The method involves chromatographing a hydrolysed urine sample with high-performance liquid chromatography and quantifying the eluting cross-reacting cannabinoids with radioimmunoassay. It has been applied to the analysis of cannabinoids in human urine obtained from subjects who had smoked delta 9-tetrahydrocannabinol and the identities of some of the cross-reacting cannabinoids have been established by gas chromatography-mass spectrometry. The method is suitable for use as a routine procedure for cannabinoid analysis in urine.
本文描述了一种用于测量尿液中大麻素的高效液相色谱-放射免疫分析法。该方法包括用高效液相色谱对水解后的尿液样本进行色谱分析，并用放射免疫分析法对洗脱的交叉反应性大麻素进行定量。它已应用于对吸食了δ9-四氢大麻酚的受试者的人尿中大麻素的分析，并且一些交叉反应性大麻素的身份已通过气相色谱-质谱法确定。该方法适合用作尿液中大麻素分析的常规程序。
