Richart C, Ruibal A, Monné J
Med Clin (Barc). 1979 Oct 10;73(6):239-41.
Plasma concentration of the carcinoembryonic antigen (CEA) was determined by radioimmunoassay in 80 patients affected with different neoplasms of the respiratory system, among which the most predominant was bronchial carcinoma. For this type of tumor the results showed a percentage of positivity of 69 percent, with a greater value in the disseminated neoplasias (81 percent) in comparison with those which were localized (48 percent). The concentrations of the antigen were greater in the metastatic tumors; in 55 percent of the cases levels above 40 ng/ml were observed. On the other hand this figure was reached only by 4 percent of the localized tumors. Values of the antigen higher than 40 ng/ml should lead to the suspicion of the existence of neoplastic widespread. Among the rest of the series the negativity noticed in all the cases of pleural mesothelioma stands out, and indicates that this type of tumors does not produce CEA.
采用放射免疫分析法测定了80例患有不同呼吸系统肿瘤患者的癌胚抗原(CEA)血浆浓度,其中最主要的是支气管癌。对于这类肿瘤,结果显示阳性率为69%,与局限性肿瘤(48%)相比,播散性肿瘤的阳性率更高(81%)。转移瘤中抗原浓度更高;55%的病例观察到水平高于40 ng/ml。另一方面,局限性肿瘤只有4%达到这个数值。抗原值高于40 ng/ml应引起对肿瘤广泛存在的怀疑。在该系列的其他病例中,所有胸膜间皮瘤病例均呈阴性,这表明这类肿瘤不产生CEA。